잠시만 기다려 주세요. 로딩중입니다.

Eccrine Syringofibroadenoma Associated with Bowen's Disease: A Case Report and Review of the Literature

Annals of Dermatology 2020년 32권 1호 p.57 ~ 63
이지수 ( Lee Ji-Su ) - SMG-SNU Boramae Medical Center Department of Dermatology

박현선 ( Park Hyun-Sun ) - SMG-SNU Boramae Medical Center Department of Dermatology
윤현선 ( Yoon Hyun-Sun ) - SMG-SNU Boramae Medical Center Department of Dermatology
조소연 ( Cho So-Yun ) - SMG-SNU Boramae Medical Center Department of Dermatology

Abstract


Eccrine syringofibroadenoma (ESFA) is a rare, benign adnexal neoplasm which usually manifests as a solitary nodule on the extremities of elderly patients. Few case reports have described an association between ESFA and carcinomas including squamous cell carcinoma, porocarcinoma, and basal cell carcinoma. A 66-year-old male presented with a pruritic, erythematous brownish solitary plaque with crusted and verrucous surface on the extensor side of the right thigh. The lesion developed 6 to 7 years ago, and had been growing slowly. Biopsy revealed anastomosing epithelial strands which were composed of 2 areas: the upper area consisting of dysplastic cells with prominent nucleoli and abundant mitoses, and the lower area consisting of oval and round cells, and occasionally small luminal ducts. Dysplastic cells comprised almost the entire epidermis but did not invade into the dermis. Benign syringofibroadenomatous lesion surrounded the dysplastic cells in the lowermost portion of the epidermis. Although it is still unclear whether ESFA undergoes malignant transformation or it is a reactive change to carcinoma, complete excision should be performed to prevent malignant transformation with unknown risk.

키워드

Basal cell carcinoma; Bowen's disease; Eccrine syringofibroadenoma; Porocarcinoma; Squamous cell carcinoma
원문 및 링크아웃 정보
  
등재저널 정보