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강직성 척추염 환자의 폐기능에 미치는 운동효과에 대한 메타분석

A Meta-analysis for the Effects of Exercise on Pulmonary Function in Patients with Ankylosing Spondylitis

근관절건강학회지 2019년 26권 2호 p.141 ~ 154
김은정 ( Kim Eun-Jeong ) - 동아대학교 대학원 간호학과

이은남 ( Lee Eun-Nam ) - 동아대학교 간호부
유은정 ( Rhu Eun-Jung ) - 동아대학교병원


Purpose: This study aimed to analyze the effects of exercise on pulmonary function in patients with ankylosing spondylitis (AS).

Methods: Randomized controlled trials (RCTs) were identified by searching MEDLINE, EMBASE, CENTRAL, and CINAHL (through Jan 2019). Three reviewers independently retrieved articles, extracted data, and assessed method-ological quality using the Cochrane’s Risk of Bias for randomized studies.

Results: Fourteen studies met the inclusion criteria with a total of 729 participants. CE (SMD 0.58, 95% CI 0.41~0.75, p<.001) and VO2peak (SMD 0.56, 95% CI 0.24~0.88, p=.001) had a significant effect on the most exercise interventions. As a secondary variable, BASFI (SMD -0.53, 95% CI -0.70~-0.37, p<.001), BASMI (SMD -0.75, 95% CI -0.92~-0.58, p<.001) showed an effect size of more than medium. However, PFT and QoL did not produce a significant results.

Conclusion: Pulmonary involvement is common in patients with AS and might have disturbed functionality and exercise modality. Exercise can be an effective intervention to improve pulmonary function in patients with AS. More attention is needed to improve the chest and spinal mobility to maintain the appropriate pulmonary function. It is also necessary to consider how to construct a patient-tailored exercise program to increase performance, accuracy and safety of exercise.


강직성 척추염; 운동; 메타분석
Ankylosing spondylitis; Exercise; Meta-analysis
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