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The Trend in Incidence and Case-fatality of Hospitalized Acute Myocardial Infarction Patients in Korea, 2007 to 2016

Journal of Korean Medical Science 2019년 34권 50호 p.322 ~ 322
김록범 ( Kim Rock-Bum ) - Gyeongsang National University Hospital Regional Cardiocerebrovascular Center

김혜심 ( Kim Hye-Sim ) - Yonsei University Wonju College of Medicine Center of Biomedical Data Science
강대룡 ( Kang Dae-Ryong ) - Yonsei University Wonju College of Medicine Department of Precision Medicine and Biostatistics
 ( Choi Ji-Yoo ) - Korea University Graduate School of Public Health Department of Health Policy and Hospital Management
최낙천 ( Choi Nack-Cheon ) - Gyeongsang National University School of Medicine Department of Neurology
황석재 ( Hwang Seok-Jae ) - Gyeongsang National University School of Medicine Department of Internal Medicine
황진용 ( Hwang Jin-Yong ) - Gyeongsang National University School of Medicine Department of Internal Medicine

Abstract


Background: The trend in the incidence of hospitalized acute myocardial infarction (AMI) and the difference between regions has not been reported in Korea since 2010. Thus, we aimed to inspect recent trends and regional differences in the incidence of AMI and case-fatality between 2007 and 2016.

Methods: Data from the medical utilization cohort from 2002 to 2016 were analyzed. New incidence of AMI was identified by checking the diagnosis code, duration of admission, type of test, treatment, and medication. Age-standardized incidence rate by gender, age group, and resident region was calculated from 2007 to 2016. Cumulative case-fatality rate was calculated until 3 years.

Results: Age-standardized incidence of hospitalized AMI decreased from 53.6 cases per 100,000 person-years in 2007 to 38.9 cases in 2011. Thereafter, the incidence gradually increased to 43.2 cases in 2016. The trend by gender and age groups was also similar to the total trend. The regional age-standardized incidence was the highest in Daegu (50.3 cases per 100,000 person-years) and the lowest in Sejong (30.2 cases), which were similar to the ischemic heart disease mortality in these regions. The 7-, 30-, and 90-days and 1- and 3-years average case-fatality over 10 years were 3.2%, 6.9%, 9.9%, 14.7%, and 22.4%, respectively.

Conclusion: Although case-fatality continuously decreased from 2007 to 2016, hospitalized AMI incidence decreased from 2007 to 2011 and gradually increased from 2011 to 2016, with marked disparity between regions. Effective preventive strategies to decrease AMI incidence are required to decrease cardiovascular disease mortality in Korea.

키워드

Acute Myocardial Infarction; Incidence Rate; Case-Fatality; Regional Differences
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