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視床下部의 電氣刺戟이 膣 및 子宮運動에 미치는 影響에 關한 實驗的 硏究

The Effect of Hypothalamic Stimulation on Motilities of Uterus and Vagina

경북의대잡지 1964년 5권 1호 p.67 ~ 95
이태호 (  ) - 경북대학교 의과대학 산부인과학교실

Abstract


With the use of the Lee´s stereotaxic apparatus, tiliti~~s of both vagina and uterus. continuous electrical stimulation has been provided at six different loci in the hypothalamus of 90 matured and nonpregnant, female rabbits and motilities of both uterus and vagina were recorded simultaneously on the kymographic recording system through an intravaginal balloon and direct balloonified uterus. The results obtained were as follows
1) By giving the electrical stimulation to the preoptic area there observed a marked increase in tone and mild decrease in frequency of vaginal motility, and marked increase in both tone and frequency of uterine motility.
2) Marked decrease in frequency and mild de-crease in tone of vaginal motility, and mild de-crease in both frequency and tone of uterine motility were noted with the anterior hypothalamic stimulation.
3) By giving the electrical stimulation to the ventromedial nucleus it became evident that tone, frequency and amplitude in motilities of both vagina and uterus were conspicuously increased.
4) With the latgral hypothalamic stimulation marked decrease in frequency and mild decrease in tone and amplitude were apparent in the mo-
5) Marked increase in tone and amplitude of vagi~ial motility and moderate decrease in frequency and increase in tone and a~.nplitude of uterine motility were observed with the posterior hypothalamic stimulation.
6) Electrical stimulation to the mammillar´y body resulted in marked decrease in frequency and rnarked increase in tone of vaginal motility and rnild decrease in frequency of uterine motility altho~rgh changes in tone and amplitude of uterine motility were not conspicuous.
7) On the basis of analysing changcs in motilities of uterus and vagina following hypothla~naic stimulation, anterior hypothalamus and lateral hypothalamus are thought most probably to be regulatory centers of parasympathetic function, whereas ventromedial nucleus and posterior hypothalamus are likely to discharge a sympathetic impulse. Preoptic area is apparently related to two functions, sympathetic in the medial part and pa,ras~´mpathetic in the lateral part. Mammillary body is considered to have relations with both s;,rmpathetic and parasympathetic functions in more complicated form.

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