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血淸 및 尿의 Mucoprotein에 關한 硏究

Studies on the Mucoprotein in Serum and Urine

경북의대잡지 1964년 5권 1호 p.120 ~ 134
이전근 (  ) - 경북대학교 의과대학 생화학교실

Abstract


The mucoprotein levels in serum and urine of ll.5 patients of various pediatric diseases were studied during the progress of each disease by means of the method of Anderson and Maclagan. The paper-electrophoretic studies were also carried- out on the mucoprotein in serum and urine of 12 cases, such as active rheumatic fever, adult cancer, tuberculosis, acute glomerulo-nephritis and typl´.~oid fever. The following results were obtained.
1. The serLim mucoprotein levels of active rheumatic fever, malignant tumor, acute glomerulo-nephritis, typhoid fever and tuberculosis were more increased than those of the healthy. Those of pertussis and r_hto~ic glomerulo-nephritis showed the normal valne< ? nd those of nephrosis, liver parenchymatous ~i:;case and malnutritiun ti-ere decreased.
2. The urine mucogroi.c~n. levels of most diseases were in parallel ~`:´, t-he serum mucoprotein levels, but those of ~ ~-;~hrosis was increased.
3. As the treatment :gas taken and the progress of diseases took to ~ tur better, the mucoprotein levels in serum =sic, urine began to recover gradually to then po-mal values, and therecovery vvas more slowly taken than that of some important cliniail sisns. In tuberculous meningitis, however, the spinal Fluid showe;l pathologic finding after the recovery ur mucoprotein levels; in serum and urine.
5. By paper-electrophoresis, the sec-um mucoprotein showed an increasing tendency in ai and a~,-globulin fraction of serum protein, and the urine mucoprotein also showed an increasing; tendency in α₂~β-globulin traction.

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