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非顯性 腎性高血壓症의 腎生檢에 依한 硏究

Study on Occult Primary Renal Hypertension by Renal Biopsy

경북의대잡지 1966년 7권 1호 p.25 ~ 34
조종수 (  ) - 경북대학교 의과대학 병리학교실

Abstract


A group of 64 younger(juvenile) hypertensive patients were studied on the interrlationship between clinical and histologic findings by renaln biopsy. All were considered to have essential (unknown causes) hypertension.
The results were as follows.
1. Percutaneous renal biopsies were performed in the selected group and 59.4 % were found to have unsuspected chronic glomerulonephritis and chronic pyelonephritis (#2.2% were chronic ~lomerulonephritis and 17.2 %were chronic pyelone phritis), 7.8% in unclassified histologic abnorma lities and 32.8% in normal histologic finding.
2. The most frequent change found in the chronic pyelonephritis group vas interstitial cell infiltation(81.8%), and 54% were found to have tubular atrophy which was characteristicallyassociated with hypertenson.
3. No significant differences were found in B. U. N. , creatinine and cholesterol level between normal tissue group and abnormal tissue group (chronic glomerulonephritis and chronic pyelonephritis), but the mean blood pressure was seen to be ele~~ ated in the group with abnormal tissue.
4. No Significant differences were found in chronic glomerulonephritis between laboratory findings (B. U. ~´. ,creatinine and cholesterol), and the grades cf glomerular damage, but mean blood pressure was seen to be elevated with the more severe glo;rerular damage.
5. Percutaneous renal biopsy appears to be a valuable ,procedure in the study of younger hypertensive patients, especially in silent prirnar5-renal disease.

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