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手術中 Lactated Ringer 輸液에 關한 臨床的 考察

The Clincal Observation of Patients infused with Lactated Ringer Solution during Surgery

대한마취과학회지 1968년 1권 1호 p.37 ~ 41
권창재 (  ) - 서울대학교 의과대학 부속병원 마취과

Abstract


Our own preliminary experiences with the use of lactated Ringer solution during major surgery heve been reported. We used 10cc/kg/hr in 40 patients throughout the operative period, and compared them with a control group of 30. Observations were made for the following; RBC, Hct, Hgb, electrolytes, and urine output.
There were no significant differences in blood constituents and electrolytes between the two groups, but considerable increase in urinary outupt was noticed in the experimental group during 24 hour post-operative period.
Blood transfusion had been done to replace blood loss and the experimental group had considerable reduction of transfused blood volume during surgery.
We accept and produce evidence for the concept, pronounced by Epstein, that decrease in functional rextra-cellular fluid is a major determinant to sodium excretion. A major limitation of post-operative sodium excretion seemed to be the acute contraction of the functional extracelluar fluid incurred by surgery.
If the losses of extra-cellular fluid were replaced during the operation, the phenomenon of sodium retention, was not seen. Neither normal saline nor 5% dextrose adequately replace the extracellular loss and kidneys do not eliminate excess water in this way. Lactated Ringer solution prevents acidosis and concomittant retention of water and sodium, and at the same time, sodium is adequately eliminated.
It appears that this is an advance in managing fluid and electrolyte balance during surgery.

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