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家兎에 있어서 妊娠이 人血淸抗體力價에 미치는 影響

The Influence of the Pregnancy on the Formation of the Human Serum-Antibody in Rabbits

대한산부인과학회지 1961년 4권 1호 p.55 ~ 57
임홍본 (  ) - 서울대학교 의과대학 산부인과학교실

Abstract


For the purpose of studying the influence of pregnancy on immune antibody production in the rabbit, the O-group serum of one and the same individual was used to immunize the pregnant and non-pregnant rabbit. The results obtained were as follows.
1) There is a great difference in immune antibody production by the human serum between the pregnant and non-pregnant rabbits. That is to say, the immune antibody titer of the pregnant rabbit is obviously lower than that of non-pregnant one.
2) It is assumed that the immune antibody production in the pregnant rabbit would be inhibited by some unknown substance or factor during pregnancy.
3) The average titer of the human serum antibody produced in the, pregnant rabbit is 4,500, whereas - that of the antibody produced in the non-pregnant one 13,000.

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