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子宮頸癌患者의 Cesium 遠隔照射治療時 放射線障害와 尿中 17-Ketosteroids 排泄量의 變動에 關하여

Radiation Sickness and Urinary Excretion of 17-Ketosteroids in Cesium Deep Therapy for Carcinoma of the Uterine Cervix

대한산부인과학회지 1965년 8권 1호 p.29 ~ 33
박문선 (  ) - 한일병원 산부인과

Abstract


Observation of radiation sickness and leucocyte count were made in 20 cases of squamous cell carcinoma of the uterine cervix, receiving Cesium deep therapy over,periods of about 40 days at the Dept. of Obst. & Gynec., Han-11 Hospital
In 7 cases of these, urinary excretion of 17-ketosteroids was determined according to the method of Drekter.
The leucocytee count and the determination of urinary excretion of 17-ketosteroids were carried´ out before and during Cesium deep therapy.
Fatigability, anorexia, nausea and vomiting, headache, dizziness, abdominal pain, insomnia, thirst. fever, pollakisuria and diarrhea were considered to be suggestive of radiation sickness. The following results were obtained:
1.) As to the radiation sickness, diarrhea is noticed in 13 cases, fatigability in 11 cases and anorexia in 10 cases, respectively. The highest incidence of these symptoms(60 per cent) is. seen on the tenth day of irradiation.
2.) Leucocytc count is decreased gradually with increasing irradiation dosage of Cesium.
3.) The urinary excretion of 17-ketosteroids begins to increase above the preirradiation levell from the begining of irradiation and reaches its highest level on the tenth day of irradiation, after which a decrease is noted. It becomes lower than preirradiation level from the thirtieth day of irradiation.

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