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姙娠時 尿中 17-Ketosteroids 및 17-Hydroxycorticosteroids値의 動態에 關하여

Fluctuations of Urinary 17-Ketosteroids and 17-Hydroxycorticosteroids in Pregnancy

대한산부인과학회지 1969년 12권 7호 p.3 ~ 8
손창수 (  ) - 서울대학교 의과대학 산부인과학교실

Abstract


The values of the urinary 17-KS and 17-OHCS were measured in 4 of non-pregnant women, 23 of normal pregnant women, 7 of normally coursed puerperal women, and 3 of women with anencephalic fetus in the last trimester of pregnancy.
The following results pointed out that we ´should include feto-placental unit as well as adrenal cortex of pregnant women as sources of production of corticoids in pregnancy.
1) There was no difference in the values of the urinary 17-KS between pregnant´ state and non-pregnant state. Of course, there was ? little change in that of the urinary 17-KS in all pregnant course.
2) The value of the urinary 17-OHCS revealed two peaks at the 24th week and 32nd week of gestation.
3) Pregnant women with anencephalic fetus resulted in declination of the urinary estriol and 17-KS with no alteration of value of the urinary 17-OHCS.

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