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放射線이 子宮頸癌細胞 染色體에 미치는 形態學的 變化

Radiological Influence on the Cancer Cell Chromosome of the Uterine Cervix

대한산부인과학회지 1970년 13권 3호 p.3 ~ 9
라건영 (  ) - 서울대학교 의과대학 산부인과학교실

Abstract


The author studied on the effects of radiation on the chromosome of the uterine cervix cancer by the method-of tissue culture. As a result, followings were obtained. 1) 24 slices of the uterine cervix cancer tissue were tried to culture. But 5 in non-radiating group, 3 in -radiating group by 200 rad, and 2 in radiating group by 400 rad were succeeded in culture. It was enough to study the chromosomal morphology.
2) The range of number of chromosomes of 236 cells in non-radiating group and-188- cells in radiating group, were varied from haploid to tetraploid, and furthermore they had stemline of hyperdiploid. The significant change of chromosome number caused by radiation was not recognized.
3) The breakage rate of chromosomal morphology of non-radiating ´group was 15.4 percent and that of radiating group was 28.4 percent. It means that there was significant difference in the morphological change of chromosome by radiation.

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