Á¶±â ºÐ¸¸µÈ ½ÖÅ Àӽſ¡¼ ºÐ¸¸ ¼ø¼¿¡ µû¸¥ ½Å»ý¾Æ È£Èí°ï¶õ ÁõÈıº ¹ß»ý¿¡ °üÇÑ ¿¬±¸
Effect of birth order on respiratory distress syndrome in preterm twin pregnancy
ÀÌÁöÀº ( Lee Ji-Eun ) - ¼º±Õ°ü´ëÇб³ Àǰú´ëÇÐ »ï¼º¼¿ïº´¿ø »êºÎÀΰúÇб³½Ç
ÃÖ¼®ÁÖ ( Choi Suk-Joo ) - ¼º±Õ°ü´ëÇб³ Àǰú´ëÇÐ »ï¼º¼¿ïº´¿ø »êºÎÀΰúÇб³½Ç
¿À¼ö¿µ ( Oh Soo-Young ) - ¼º±Õ°ü´ëÇб³ Àǰú´ëÇÐ »ï¼º¼¿ïº´¿ø »êºÎÀΰúÇб³½Ç
±èÁ¾È ( Kim Jong-Hwa ) - ¼º±Õ°ü´ëÇб³ Àǰú´ëÇÐ »ï¼º¼¿ïº´¿ø »êºÎÀΰúÇб³½Ç
³ëÁ¤·¡ ( Roh Cheong-Rae ) - ¼º±Õ°ü´ëÇб³ Àǰú´ëÇÐ »ï¼º¼¿ïº´¿ø »êºÎÀΰúÇб³½Ç
Ãֵμ® ( Choi Doo-Seok ) - ¼º±Õ°ü´ëÇб³ Àǰú´ëÇÐ »ï¼º¼¿ïº´¿ø »êºÎÀΰúÇб³½Ç
±èÇü¼± ( Kim Hyoung-Sun ) - ¼º±Õ°ü´ëÇб³ Àǰú´ëÇÐ »ï¼º¼¿ïº´¿ø »êºÎÀΰúÇб³½Ç
Abstract
¸ñÀû: ½ÖÅ Àӽſ¡¼ ½Å»ý¾Æ È£Èí°ï¶õ ÁõÈıºÀÇ ¹ß»ý¿¡ ´ëÇØ Ãâ»ý ¼ø¼°¡ ¾î¶°ÇÑ ¿µÇâÀ» ÁÖ´Â Áö¸¦ Á¶±â ºÐ¸¸ÀÇ ¿øÀο¡ µû¶ó ºÐ¼®ÇϰíÀÚ ÇÏ¿´´Ù.
¿¬±¸¹æ¹ý: 1997³â 1¿ùºÎÅÍ 2005³â 4¿ù±îÁö Ãâ»ýÇÑ 24ÁÖºÎÅÍ 34ÁÖ »çÀÌÀÇ 163½ÖÀÇ ½Ö»ý¾Æ¿¡ ´ëÇÑ ÈÄÇâÀû ºÐ¼®À» ½ÃÇàÇÏ¿´´Ù. ¿¬±¸ ´ë»ó±ºÀ» Á¶±â ÁøÅ뱺, Á¶±â ¾ç¸·ÆÄ¼ö±º, ±âŸ ¸ð¼º-ÅÂ¾Æ ÀûÀÀÁõ±ºÀÇ 3±ºÀ¸·Î ºÐ·ùÇÏ¿´´Ù. Àڱó» žƻç¸ÁÀ̳ª ÁßÁõÀÇ ÅÂ¾Æ ±âÇüÀº Á¦¿ÜÇÏ¿´À¸¸ç, ´ë»ó±ºÀÇ 88.3%¿¡¼ Á¦¿Õ Àý°³ ºÐ¸¸ÀÌ ½ÃÇàµÇ¾ú´Ù. Àǹ«±â·Ï °ËÅ並 ÅëÇÏ¿© ÁÖ¿ä ½Å»ý¾Æ ÀÌȯ (½Å»ý¾Æ È£Èí°ï¶õ ÁõÈıº, ±â°üÁöÆóÀÌÇü¼ºÁõ, ³ú½Ç³» ÃâÇ÷, ±«»ç¼º Àå¿°, Á¶±â ½Å»ý¾Æ ÆÐÇ÷Áõ)ÀÇ ¹ß»ý ¿©ºÎ¸¦ Á¶»çÇÏ¿´À¸¸ç °¢ ±ºÀÇ Á¦ 2 ½Ö»ý¾Æ¿¡ ´ëÇÑ ¿¹ÈÄ´Â Á¦ 1 ½Ö»ý¾Æ¿Í Á÷Á¢ ºñ±³ÇÏ¿´´Ù.
°á°ú: Àüü ´ë»ó±º¿¡¼ Á¦ 1 ½Ö»ý¾Æ°¡ Á¦ 2 ½Ö»ý¾Æ¿¡ ºñÇÏ¿© ½Å»ý¾Æ È£Èí°ï¶õ ÁõÈıºÀÇ ¹ß»ýÀÌ À¯ÀÇÇÏ°Ô ³·¾Ò°í (p=0.02), ƯÈ÷ Á¶±â ¾ç¸·ÆÄ¼ö±º¿¡¼ Á¦ 1 ½Ö»ý¾ÆÀÇ ½Å»ý¾Æ È£Èí°ï¶õ ÁõÈıº ¹ß»ýÀÌ ¼ºº°ÀÇ Â÷À̸¦ º¸Á¤ÇÏ°íµµ À¯ÀÇÇÏ°Ô °¨¼ÒÇÏ¿´´Ù (p=0.001). ±×·¯³ª Á¶±â ÁøÅ뱺°ú ¸ð¼º-ÅÂ¾Æ ÀûÀÀÁõ±º¿¡¼´Â µÎ ½Ö»ý¾Æ°£ ½Å»ý¾Æ È£Èí°ï¶õ ÁõÈıº ¹ß»ýÀÇ À¯ÀÇÇÑ Â÷À̰¡ ¾ø¾ú´Ù. ½Å»ý¾Æ È£Èí°ï¶õ ÁõÈıºÀ» Á¦¿ÜÇÑ ½Å»ý¾Æ ÀÌȯÀ² ¹× »ç¸Á·üÀº Àüü ´ë»ó±º ¹× Á¶±â ÁøÅ뱺, Á¶±â ¾ç¸·ÆÄ¼ö±º ±×¸®°í ¸ð¼º-ÅÂ¾Æ ÀûÀÀÁõ±º¿¡¼ µÎ ½Ö»ý¾Æ°£ À¯ÀÇÇÑ Â÷À̰¡ ¾ø¾ú´Ù.
°á·Ð: Á¶±â ¾ç¸·ÆÄ¼ö±º¿¡¼ Á¶±â ÁøÅ뱺 ¹× ±âŸ ¸ð¼º-ÅÂ¾Æ ÀûÀÀÁõ±º°ú ´Þ¸® Á¦ 1 ½Ö»ý¾Æ¿¡¼ ½Å»ý¾Æ È£Èí°ï¶õ ÁõÈıºÀÇ
¹ß»ý ºóµµ°¡ Á¦ 2 ½Ö»ý¾Æ¿¡ ºñÇØ À¯ÀÇÇÏ°Ô °¨¼ÒÇÏ¿´´Ù.
Objective: To determine the effect of birth order on development of respiratory distress syndrome (RDS) in twin pregnancy according to the cause of preterm birth.
Methods: A retrospective analysis of 163 live born twin pairs who delivered at 24-34 weeks of gestation from January 1997 to April 2005 was done. Intrauterine fetal deaths or cases with severe fetal malformations were excluded. Subjects were categorized into three groups according to the cause of preterm birth: a preterm labor (PTL) group, a preterm premature rupture of membrane (PPROM) group and other maternal-fetal indication group. One hundred forty four twin pairs (88.3%) were delivered by cesarean delivery. We analyzed the incidence of RDS and other morbidities such as bronchopulmonary dysplasia, intraventricular hemorrhage, necrotizing enterocolitis and early neonatal sepsis in above three groups. Each second-twin was compared for specific outcomes directly with its first-twin birth mate.
Results: Overall, the first-born twin had less RDS compared to the second-born twin (p=0.02). Specifically, a reduced incidence of RDS of the first-born twin was significant in the PPROM group, regardless of neonatal sex (p=0.001). In other groups, there was no correlation between birth order and RDS. Except for RDS in the PPROM group, neonatal mortality and other morbidities were not significantly different between the first- and second-born twins.
Conclusion: There is a significant decreased risk of RDS in the first-born twins from PPROM, but not from PTL or other indications.
Ű¿öµå
½ÖÅ ÀÓ½Å;ºÐ¸¸ ¼ø¼;Á¶±â ¾ç¸·ÆÄ¼ö;½Å»ý¾Æ È£Èí°ï¶õ ÁõÈıº;½Å»ý¾Æ ÀÌȯ
twin pregnancy;birth order;preterm premature rupture of membrane;respiratory distress syndrome;Neonatal morbidity
KMID :
0358420070500060872
DOI :
¿ø¹® ¹× ¸µÅ©¾Æ¿ô Á¤º¸
µîÀçÀú³Î Á¤º¸