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A Granular Cell Tumor Located in the Gastric Cardia

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±è±¤ÇÏ ( Kim Gwang-Ha ) - ºÎ»ê´ëÇб³ ÀÇÇÐÀü¹®´ëÇпø ³»°úÇб³½Ç
±è¹Ì¶ó ( Kim Mi-Ra ) - ºÎ»ê´ëÇб³ ÀÇÇÐÀü¹®´ëÇпø ³»°úÇб³½Ç
Á¤È«·Ä ( Jeong Hong-Ryul ) - ºÎ»ê´ëÇб³ ÀÇÇÐÀü¹®´ëÇпø ³»°úÇб³½Ç
Á¤ÀçÈÆ ( Cheong Jae-Hoon ) - ºÎ»ê´ëÇб³ ÀÇÇÐÀü¹®´ëÇпø ³»°úÇб³½Ç
¹ÚÂùÈ£ ( Park Chan-Ho ) - ºÎ»ê´ëÇб³ Àǰú´ëÇÐ ³»°úÇб³½Ç
À̼±¹Ì ( Lee Sun-Mi ) - ºÎ»ê´ëÇб³ ÀÇÇÐÀü¹®´ëÇпø ³»°úÇб³½Ç
±èÅ¿À ( Kim Tae-Oh ) - ºÎ»ê´ëÇб³ ÀÇÇÐÀü¹®´ëÇпø ³»°úÇб³½Ç
ÇãÁ¤ ( Heo Jeong ) - ºÎ»ê´ëÇб³ ÀÇÇÐÀü¹®´ëÇпø ³»°úÇб³½Ç
°­´ëȯ ( Kang Dae-Hwan ) - ºÎ»ê´ëÇб³ ÀÇÇÐÀü¹®´ëÇпø ³»°úÇб³½Ç
¼Û±Ù¾Ï ( Song Geun-Am ) - ºÎ»ê´ëÇб³ ÀÇÇÐÀü¹®´ëÇпø ³»°úÇб³½Ç
Á¶¸ù ( Cho Mong ) - ºÎ»ê´ëÇб³ ÀÇÇÐÀü¹®´ëÇпø ³»°úÇб³½Ç

Abstract

°ú¸³¼¼Æ÷Á¾Àº ÇǺÎ, ±¸°­, À¯¹æ µî¿¡¼­ ¹ß°ßµÇ´Â ¾ç¼º Á¾¾çÀ¸·Î, ¸é¿ªÁ¶Á÷ÇÐÀûÀ¸·Î S-100 ´Ü¹é µî¿¡ ¿°»öµÇ´Â ¼Ò°ßÀ¸·Î º¸¾Æ, ½Å°æ¼¼Æ÷¿¡¼­ À¯·¡ÇÑ °ÍÀ¸·Î ¾Ë·ÁÁ® ÀÖ´Ù. À§Àå°ü ¹ß»ý·üÀº ³·À¸¸ç, ±× Áß¿¡¼­ È£¹ßÇÏ´Â ºÎÀ§´Â ½ÄµµÀ̸ç, À§¿¡¼­ ¹ß°ßµÇ´Â °æ¿ì´Â ¸Å¿ì µå¹°´Ù. ÀúÀÚµéÀº 29¼¼ ¿©ÀÚ¿¡¼­, °ËÁø ¸ñÀûÀ¸·Î ½ÃÇàÇÑ ³»½Ã°æ °Ë»ç¿¡¼­ ¿ì¿¬È÷ ¹ß°ßµÈ À§ºÐ¹®ºÎ Á¡¸·ÇÏ Á¾¾çÀ» ³»½Ã°æÀ¸·Î ÀýÁ¦ ÈÄ, °ú¸³¼¼Æ÷Á¾À¸·Î È®ÁøÇÑ 1¿¹¸¦ º¸°íÇϰíÀÚ ÇÑ´Ù.

First described in 1926 by Abrikossoff, a granular cell tumor is a benign lesion and commonly involves the skin, connective tissue, and breast, but rarely the esophagus. The origin of granular cell tumors is controversial. The tumor is thought to arise from a Schwann cell origin, based on characteristics such as the positive expression of S-100 protein determined by immunohistochemical staining. A 29-year-old female was referred from the local clinic because of a polypoid lesion in the gastric cardia. After performing endoscopy and endoscopic ultrasonography, a 1.5 cm submucosal tumor covered with normal mucosa was found in the gastric cardia. Endoscopic mucosal resection revealed a tumor that initiated in the esophagus, and grew into the cardia. Immunohistochemical analysis revealed strong positive staining for S-100 protein, confirming the presence of a granular cell tumor. (Korean J Gastrointest Endosc 2008;36:22-26)

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Granular cell tumor; Gastric cardia; Endoscopic mucosal resection
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KCI
KoreaMed
KAMS