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Sodium monofluoroncetate (Compound 1080) 중독에 관한 가토의 병리해부학적 연구

PATHOLOGIC STUDIES ON SODIUM MONOFLUOROACETATE ( COMPOUND 1080 ) POISONING IN RABBITS

대한수의학회지 1961년 1권 1호 p.65 ~ 70
김화식 (  ) - 경북대학교 수의병리학교실

Abstract


Many losses in domestic animals have been reported in this country, since sodium monofluoroacetate (Compound 1080) was used as a rodenticide.
Lesions described inclubed multiple petechiae in epi- and endocardium, lung and intestinal mucosa, or superficial necrosis of the gastric mucosa.
In this studies as to the poisoning 7 rabbits were administered 0.6㎎ (Group Ⅰ). 0.4㎎ (GroupⅡ), and 0.3㎎ (GroupⅢ) of sodium monofluoroacetate per kilogram of body weight, and the results obtained were as follows:
In addition to the changes mentioned above fatty degeneration in central parts of hepatic lobule or nut meg liver, haemorrhagic feci in cerebral cortex and leptemeninges and fatty degeneration in kidney and cardiac muscles were found.

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