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방사성옥도 (I131) 의 주입량이 기니픽 갑상선에의 섭취 및 방출률에 미치는 영향에 관한 연구

Studie son the Effects of Injected Amount of I131 in Uptake and Release Rate by Thyroid in Guinea Pigs

대한수의학회지 1966년 6권 1호 p.24 ~ 30
심상칠 (  ) - 서울대학교 농과대학

이흥식 (  ) - 서울대학교 농과대학
정영채 (  ) - 충남대학교 농과대학

Abstract


In order to observe the effect of the injected radioactive iodine-I^(131) on the uptake in thyroid of normal male guinea pigs and P.B.I^(131) conversion ratio of I^(131) in serum, 24 matured male guinea pigs were divided in 4 groups and 35μc, 70μc, 140μc and 280μc per ㎏ of body weight respectively were injected subcutaneously.
1. The uptake rates of radioactveiodine-I^(131) by external counts of thyroidal uptake reached the maximum level of uptake in 24 hours after injection.
2. As the injected amount increases, the uptake rates of maximum levels and release rate were increased.
3. Uptake rate in the removed thyroid have shown no statistical in the 35μc and 70μc groups of injected guinea pigs.
4. There was no statistical significance in 140μc and 280μc groups of injected guinea pigs.
5. P.B.I^(131) conversion ratio of I^(131) in serum was not in proportion to injected amounts: 61.0%(35), 70.2%(70), 75.3%(140) and 64.8%(280).

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