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일측 갑상선 제거가 I131 의 대사에 미치는 영향

Metabolic Change of I131 in Unilatearl Thyrodectmized Rabbits

대한수의학회지 1967년 7권 2호 p.35 ~ 41
정영채 (  ) - 충남대학교 농과대학

장병표 (  ) - 서울대학교 농과대학
권종국 (  ) - 서울대학교 농과대학
이영소 (  ) - 서울대학교 농과대학

Abstract


In these studies, the relationship of the thyroid function of normal and unilateral thyroidectomized rabbits. were studied. I^(131) uptake rate of the thyroid gland, the concentration of the PBI^(131) and I^(131) in the blood, erum PB^(131) conversion ratio, and the thyroidal I^(131) release rate in ten rabbits were mesured following a single intramuscular injection of 10 μci of I^(131).
1. The thyroidal I^(131) uptake rate in the treated group were 5,06, 8.58, 6.46, and 6.54% in 12, 36, 60 and 85 hrs., respectively, after injection of I^(3). The uptake rate were significantly differrenciate between the two groups.(P<0.05)
2. The PBl^(3) conversion ratios were 9.87, 15.63, 41.01, 66.25 end 66.25% in 12, 36, 84, 132, 180 hrs, respectively, after injection of I^(131). No significant difference was observed between the groups.
3. The concentration of PBI^(131) and I^(131) in the blood were significant between the groups.
4. The excretion rate of I^(131) in urine was not significant between two groups, but the excretion of I^(131) in the treated group was higher than that of the control group.
5. The exrcetion rate of I^(131) in feces in the treated group were significantly higher than the control group. (p<0.01)

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