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翡 Marek ü

CELL CULTURE STUDIES OF MAREKS DISEASE ETIOLOGICAL AGENT

Ѽȸ 1969 9 2ȣ p.1023 ~ 1062
ȣ (  ) - Chunchon Aricultural College

Abstract

ܻͮ "ܻͮ"ӿ ߵǾ Marek ܻ ó ͮߧ ־ ʵǴ ܻ Ǹ ϰ ִ. ϰ Юټ ͮߧ ۡ Ҿ ̵ ܻ ذ ̸ Φ Ҵ ϱڸ Marek ܻ , ϹǷμ Marek ܻ ګִ ܻ ϳ ϰԲ Ǿ.
⵿ȿ ̵ ܻ μϿ Ӱ ִ ϼ ̷Ǿ ߿ ѱ "ܻͮ"̶ ӿ ߵǾ ̵ ڪ ΰ ٥ ܻ ̴. ̸߾ ׾ ϴ ̵ ܻ  ù° ڨ ׵ ܻ 信 ̸, ̰ ܻ׾ ־ κ Ǵ ̴.
׷ ̿Ͱ  ٥ Φ Ҵ ٸ Mare kܻ ܻ, ڸ ϼӥ Լء ׿ Ͽ Marek ܻܻ ͷμ herpes virus ̸ۡ, ϹǷμ ̷. ߾ 1954Ҵ ҭ, ܻ ϼ٥ Ͽ ⿡ , ӹ Ͽ, ܻ myxovirus ܻͮ ٸ ϰ̶ 鿡 Ͽ Ǿ Դ. ׿ Marek ܻ ܻ ӫͭ ֱ ϳ ܻ ϼ ŭ Ϣ ̷Ͽٰ Marek ܻ herpes virus μ(ܻμ) ϼ ǰִ ̴.
Marek ܻܻ ϱ ŰǷμ GF Marek ܻ(Keny et al., 1964) CR-64 Marek ܻ(Staples, 1964) ܻ ϼ٥Ͽ ܻ , μ ư Marek ܻ ٸ ܻ , Ǵ ܻμ herpes virus Ǿ, ̿Τ .
GF CR-64 Marek ܻ ͮ Ӥ(د)࿡ ־ ܻ virus ѷ ܨ ()ܻ Ÿ ()ܻ (Ų) ުӤ׿ ʥϹǷμ() Ю ӹ()Ǿ. ͮ ࿡ ۵ɼ ־ ͮ׿, ฦ Ͽ ƹ ܨ(CPE) Ҽ . Marek ܻ ͮκ buffy coat(Ϲ-)ݩ ͮ࿡ ϹǷμ Ȱ ܨ Ÿ ٸ 쿡 ܻ⦴ Marek ܻͮκ ׿ Ͽ ξ ⦷ Ÿ. ߾ μ Marek ܻ GFܻ CR-64 ܻ࿡ ƹ ̸ۡ .
̿Ͱ ܻ п ̿ ϰ ־ յǾִ κ ܻ ϴ (ܻ) ʦϿ, ͩ(ӹ)ڪ ڪ . ࿡ ־ ܨ, ު virus ̷ ܨ plaqueΰ virus ܨܻ(focus) κǿ ͮ߾ Rous sarcoma virus װͿ Ͽ.
ܻ ܻ ͪ⦵ ܻ࿡ μμ Ͽ.
ܻ ⿡ , Ү ܬ ⿡ virus ߫ܬ ̵ ܻ ܻ B herpes virus װͰ п Ÿ, ⿡ ۰ Ͽ ܻ׵ ܻͮ/ virus PPLO μμ .
ڰκ herpes virus viusأ ܻ/Marek ܻ ͮ ̿ Marek ܻ ܻܨ ͮ ۡ, ߯ ͮκ ׿ ־ ٥ ܨ ܻ() Ǹ ޽ ־.
̿Ͱ ̿μ ฦ ݽŰ ʰ ܨ(transformation) Ű ̵ Marek ܻܻ װ̸, B herpes virus ϴ - ӨҵǾ, ̵ virus ͵ (oncogenicity) ϰ ҵǾ.

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