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高血壓症 患者의 動脈硬化에 關한 硏究

Studies on the Vascular Sclerosis in Hypertensive Disease

대한안과학회지 1965년 6권 2호 p.11 ~ 23
이상욱 (  ) - 가톨릭의대 안과

Abstract


The author investigated 100 hypertensive patients (199 eyes) on their brachial blood pressure, ophthalmic blood pressure, Fritz´s index, sclerotic changes in retinal vessels, and P.S.P. test. The vascular changes of the retina were classified according to the Keith-Wagener scheme, and the sclerotic changes were represented by the point system.
For the evaluation of circulatory, status of the carotid system, Ts/Td-carotis ratio and cerebrovascular resistance (CVR) were also calculated.
The relationships between these data were studied and their results were as follows:
(1) There was a linear correlation between mean ophthalmic blood pressure and mean brachial blood pressure, the correlation coefficient being plus 0.83.
(2) There was also a linear relationship between fundus changes and mean ophthalmic blood pressure. The more advanced the grade of Keith-Wagener classification and the sclerotic changes, the higher the mean ophthalmic blood pressure. The rise of the mean ophthalmic blood pressure was. more marked in K-W grade III, IV, and in grade IV sclerosis.
(3) There was a close relationship between P.S.P. test, mean ophthalmic blood pressure and brachial blood pressure. The renal function was disturbed in patients with higher mean ophthalmic blood pressure.
(4) The decrease of Ts/Td -carotis was always accompanied by the increase of Fritz´s index, severity, of sclerotic changes in the retina and advancement of the grade of K-W. classification.
(5) In patients with normal P. S. P. value, there was no single case of advanced sclerosis (more that (10 points of sclerosis). Ts/Td-carotis ratio was generally over 1.0. In patients with low P.S.P.-value, however, the retinal vascular sclerosis showed more. marked changes, and . Ts/Td-carotis ratio fallen below 1.0.

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