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Long-Term Results of Descemet¡¯s Stripping Automated Endothelial Keratoplasty in Korea

´ëÇѾȰúÇÐȸÁö 2010³â 51±Ç 11È£ p.1431 ~ 1437
ÀÌÁؼº ( Lee Jun-Sung ) - Àü³²´ëÇб³ Àǰú´ëÇÐ ¾È°úÇб³½Ç

¹Ú¿µ°É ( Park Yeoung-Geol ) - Àü³²´ëÇб³ Àǰú´ëÇÐ ¾È°úÇб³½Ç
À±°æÃ¶ ( Yoon Kyung-Chul ) - Àü³²´ëÇб³ Àǰú´ëÇÐ ¾È°úÇб³½Ç

Abstract

¸ñÀû:±¹³»¿¡¼­ µ¥½º¸Þ¸·¹Ú¸® °¢¸·³»ÇÇÃþÆÇÀ̽ļúÀ» ½ÃÇà¹ÞÀº ȯÀÚµéÀÇ Àå±â ÀÓ»ó °á°ú¸¦ ¾Ë¾Æº¸°íÀÚ ÇÏ¿´´Ù.

´ë»ó ¹× ¹æ¹ý:º»¿ø¿¡¼­ ¼öÆ÷°¢¸·º´ÁõÀ¸·Î µ¥½º¸Þ¸·¹Ú¸® °¢¸·³»ÇÇÃþÆÇÀ̽ļúÀ» ½ÃÇà¹ÞÀº ȯÀÚ Áß 18°³¿ù ÀÌ»ó °æ°ú °üÂûÇÏ¿´´ø 7¸í(7¾È) À» ´ë»óÀ¸·Î ¼ö¼ú Àü, ÈÄÀÇ ÃÖ´ë±³Á¤½Ã·Â, ±¼ÀýÀÌ»ó ¹× ³­½Ã°ª, °¢¸·³»ÇǼ¼Æ÷¼ö, °¢¸·µÎ²² µîÀ» ÈÄÇâÀûÀ¸·Î ºÐ¼®ÇÏ¿´´Ù.

°á°ú:Æò±Õ °üÂû ±â°£Àº 19.9 ¡¾ 2.9 (18~24)°³¿ùÀ̾úÀ¸¸ç Æò±Õ ¿¬·ÉÀº 61.42 ¡¾ 10.13 (46~76)¼¼¿´´Ù. Àüü 7¾È Áß 6¾È(85.7%)¿¡¼­ ¼º °øÀûÀÎ »óŸ¦ º¸¿´°í ÃÖ´ë±³Á¤½Ã·Â(logMAR)Àº ¼ö¼ú Àü 1.62 (Áß¾Ó°ª)¿¡¼­ ¼ö¼ú ÈÄ 1°³¿ù° 1.15 (Áß¾Ó°ª) (p = 0.027)·Î À¯ÀÇÇÑ È£ÀüÀ» º¸¿´À¸¸ç ÃÖÁ¾ °æ°ú °üÂû ½Ã±îÁö À¯ÁöµÇ¾ú´Ù. ¼ö¼ú ÈÄ 18°³¿ùÀÇ ±¼ÀýÀÌ»ó ¹× ³­½Ã°ªÀº ¼ö¼ú Àü°ú ºñ±³ÇÏ¿© À¯ÀÇÇÑ Â÷À̸¦ º¸ÀÌÁö ¾Ê¾Ò ´Ù. 1¾È¿¡¼­ ÀÌ½Ä½ÇÆÐ¸¦ º¸¿© ¼ö¼ú ÈÄ 12°³¿ù° ÀüÃþ°¢¸·À̽ļúÀ» ½ÃÇàÇÏ¿´´Ù.

°á·Ð:Àå±â °æ°ú °üÂû °á°ú µ¥½º¸Þ¸·¹Ú¸® °¢¸·³»ÇÇÃþÆÇÀ̽ļúÀº ºü¸¥ ½Ã·Â ȸº¹À» º¸¿´°í ±¼Àý ¹× ³­½Ã°ªÀÇ º¯È­°¡ Àû¾úÀ¸¸ç, °¢¸·³»ÇÇ ºÎÀüÁõ ȯÀÚ¿¡ ÀÖ¾î ¼±ÅÃÇÒ ¼ö ÀÖ´Â ÁÁÀº ¼ö¼ú¹ýÀ̶ó »ý°¢µÈ´Ù.
Purpose:To evaluate the long-term results of Descemet¡¯s stripping automated endothelial keratoplasty in Korea (DSAEK).

Methods:Seven patients with bullous keratopathy who underwent DSAEK and who were followed-up for more than 18 months were reviewed retrospectively. Best corrected visual acuity, refraction, corneal thickness, and endothelial cell count were examined before and after surgery.

Results:The mean follow-up period was 19.9 ¡¾ 2.9 months (18 to 24 months), and the mean age was 61.42 ¡¾ 10.13 years (46 to 76 years). Six patients (85.7%) showed successful results after surgery. Best corrected visual acuity (logMAR) was significantly improved from 1.62 (median) to 1.15 (median) (p = 0.027) at one month after surgery and was maintained until the final follow-up period. There were no statistical differences in spherical ametropia or astigmatism before or 18 months after the operation. Graft failure was observed in one case, in which penetrating keratoplasty was performed 12 months after DSAEK.

Conclusions:Long term results of DSAEK showed fast visual recovery, low ametropia and astigmatism. DSAEK may be a good option for the surgical management of corneal endothelial disease.

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DSAEK; Graft failure; Refractive change
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KCI
KoreaMed
KAMS