°íµî°¢¸·Ç¥¸é¿¬¸¶±¼Àý¼ö¼ú ÈÄ °¢¸·Áö°¢, ´«¹°¸· ¹× ¾È±¸Ç¥¸éÀÇ º¯È
Changes in Corneal Sensation, Tear Film Stability and Ocular Surface after Advanced Surface Ablation
À̺´Èñ ( Lee Byeong-Hee ) - Á¦ÀϾȰúº´¿ø
±èÀºÁÖ ( Kim Eun-Joo ) - Á¦ÀϾȰúº´¿ø
±èÁöÇö ( Kim Jee-Hyun ) - Á¦ÀϾȰúº´¿ø
À̱¤ÀÚ ( Lee Gwang-Ja ) - Á¦ÀϾȰúº´¿ø
À̱Կø ( Lee Kyoo-Won ) - Á¦ÀϾȰúº´¿ø
¹Ú¿µÁ¤ ( Park Young-Jeung ) - Á¦ÀϾȰúº´¿ø
Abstract
¸ñÀû: °íµî°¢¸·Ç¥¸é¿¬¸¶±¼Àý¼ö¼ú(advanced surface ablation)ÈÄ ´«¹°¸·, °¢¸·Áö°¢, ¾È±¸Ç¥¸éÀÇ º¯È¸¦ ¾Ë¾Æº¸°íÀÚ ÇÏ¿´´Ù. ´ë»ó°ú ¹æ¹ý: °íµî°¢¸·Ç¥¸é¿¬¸¶±¼Àý¼ö¼úÀ» ½ÃÇà ¹ÞÀº 25¸í 50¾ÈÀ» ´ë»óÀ¸·Î ¼ú Àü, ¼ú ÈÄ 2ÁÖ, 1 ? 2 ? 3 ? 6°³¿ù¿¡ ´«¹°¸·ÆÄ±«½Ã°£, ´«¹°ºÐ ºñ°Ë»ç, °¢¸·Ç¥¸éÇü±¤¿°»ö°Ë»ç, °¢¸·Áö°¢°Ë»ç, Ocular surface disease index (OSDI) ±×¸®°í °á¸·¾ÐÈç¼¼Æ÷°Ë»ç¸¦ ½ÃÇàÇÑ ÈÄ ¼ú Àü°ú ºñ±³ ºÐ¼®ÇÏ¿´´Ù. °á°ú: OSDI´Â ¼ú ÈÄ 2ÁÖ° ÀÇ¹Ì ÀÖ°Ô °¨¼ÒÇÏ¿´°í °¢¸·Áö°¢Àº ¼ú ÈÄ 1°³¿ù±îÁö °¨¼ÒÇÏ¿´´Ù(p£¼0.05). ´«¹°¸·ÆÄ±«½Ã°£Àº ¼ú ÈÄ 2ÁÖ-1´Þ±îÁö ´«¹°ºÐºñ°Ë»ç´Â ¼ú ÈÄ 2-3°³¿ù° ÀÇ¹Ì ÀÖ°Ô °¨¼ÒÇÏ¿´´Ù(p£¼0.05). °¢¸·Ç¥¸éÇü±¤¿°»ö°Ë»ç»ó ¼ú ÈÄ 2ÁÖ° ÀÇ¹Ì ÀÖ°Ô Áõ°¡ÇÏ¿´´Ù(p£¼0.05). °á¸·¾ÐÈç¼¼Æ÷°Ë»ç¿¡¼ ¼úÀܼ¼Æ÷¹Ðµµ´Â ¼ú ÈÄ 1´Þ±îÁö ÀÇ¹Ì ÀÖ°Ô °¨¼ÒµÇ¾ú°í ÆíÆò¼¼Æ÷ È»ýÁ¤µµ´Â ¼ú ÈÄ 2°³¿ù±îÁö ÀÇ¹Ì ÀÖ°Ô Áõ°¡µÇ ¾ú´Ù(p£¼0.05). °á·Ð: °íµî°¢¸·Ç¥¸é¿¬¸¶±¼Àý¼ö¼úÀº ´«¹°¸·, °¢¸·Áö°¢, ¾È±¸Ç¥¸é¿¡ ¼ö¼ú ÈÄ 3°³¿ù±îÁö ¿µÇâÀ» ÁÙ ¼ö ÀÖ¾î Æ¯È÷ ¼ö¼ú ÈÄ Ãʱ⠾ȱ¸°ÇÁ¶Áõ Ä¡·á°¡ Áß¿äÇÒ °ÍÀ¸·Î »ý°¢ÇÑ´Ù.
Purpose: To evaluate the changes in tearfilm, corneal sensation and ocular surface after advanced surface ablation. Methods: Tearfilm break-up time (BUT), Schirmer test without local anesthesia, fluorescein staining, corneal sensitivity test, ocular surface disease index (OSDI), and conjunctival impression cytology were evaluated in 50 eyes of 25 patients who underwent advanced surface ablation preoperatively and postoperatively at 2 weeks and at 1, 2, 3, and 6 months. Each value was compared to the preoperative value. Results: OSDI diminished by 2 weeks postoperatively, and corneal sensation diminished by 1 month postoperatively (p < 0.05). There were significant decreases in BUT by 2 weeks to 1 month postoperatively as well as decreases in the Schirmer test by 2 to 3 months postoperatively (p < 0.05). Fluorescein staining increased at 2 weeks postoperatively (p < 0.05). Goblet cells decreased substantially by 1 month postoperatively and conjunctival squamous metaplasia increased significantly by 2 months postoperatively (p < 0.05). Conclusions: Advanced surface ablation may affect tearfilm, corneal sensation and ocular surface up to 3 months postoperatively. Early treatment of dry eye syndrome following advanced surface ablation should strongly be considered.
Ű¿öµå
Advanced surface ablation;Dry eye;Impression cytology
KMID :
0360220130540030408
DOI :
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