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항암화학요법으로 인한 증상에 대한 반하사심탕의 효과 : 체계적 문헌고찰

The Effect of Banhasasim-tang in the Treatment of Chemotherapy-induced Symptoms: A Systematic Review

대한한방내과학회지 2019년 40권 4호 p.663 ~ 674
안수빈 ( Ahn Su-Bin ) - 우석대학교 한의과대학 한의학과

이가영 ( Lee Ga-Young ) - 우석대학교 한의과대학 한의학과
황현호 ( Hwang Hyeon-Ho ) - 우석대학교 한의과대학 한의학과
정민정 ( Jeong Min-Jeong ) - 우석대학교 한의과대학 소아과학교실
장인수 ( Jang In-Soo ) - 우석대학교 한의과대학 한방내과학교실


Objective: The purpose of this study was to investigate (using a systematic review) the effect of Banhasasim-tang in the treatment of chemotherapy-induced symptoms.

Method: A systematic review was conducted to identify the effect of Banhasasim-tang for chemotherapy-induced symptoms. Electronic databases were used, including such as PubMed, Cochrane, CNKI, Wanfang, CiNii, J-STAGE, NDSL, and OASIS. Among others, the main search terms included “cancer”, “Banhasasim-tang”, “Banxia Xiexin Tang”, and “Hangeshashin-to”. This study only included randomized controlled trials (RCTs).

Results: A total of 14 RCTs were selected. They all identified the effect of Banhasasim-tang in the treatment of chemotherapy- induced symptoms such as nausea, vomiting, and diarrhea. In addition, five of the studies evaluated the preventive effect of Banhasasim-tang on the symptoms.

Conclusion: An analysis of 14 RCTs showed that Banhasasim-tang for chemotherapy-induced symptoms might be effective not only for treatment but also for prevention. However, due to the low quality and number of the selected original articles, the significance of this conclusion is somewhat limited. It is hoped that more systematic and rigorous clinical trials will be conducted.


cancer; Banhasasim-tang; chemotherapy; systematic review
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