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감수(甘遂),과체(瓜?)의 임상활용에 관한 후향적 차트리뷰

A Retrospective Chart Review of the Clinical Use of Euphorbia kansui Radix, Melonis Calyx

대한한방내과학회지 2019년 40권 6호 p.1015 ~ 1025
김동현 ( Kim Dong-Hyun ) - 경희대학교 한의과대학 부속한방병원 신장내분비내과

노지원 ( Noh Ji-Won ) - 경희대학교 한의과대학 부속한방병원 신장내분비내과
정수민 ( Jeong Su-Min ) - 경희대학교 한의과대학 부속한방병원 신장내분비내과
안세영 ( Ahn Se-Young ) - 경희대학교 한의과대학 부속한방병원 신장내분비내과
안영민 ( Ahn Young-Min ) - 경희대학교 한의과대학 부속한방병원 신장내분비내과
이병철 ( Lee Byung-Cheol ) - 경희대학교 한의과대학 부속한방병원 신장내분비내과
유정화 ( Yoo Jung-Hwa ) - 경희대학교 한의과대학 부속한방병원 신장내분비내과

Abstract


Objectives: There have been many studies reporting the clinical value of Euphorbia kansui Radix or Melonis Calyx, but few systematic studies of the changes that may occur after taking such herbal medication. This study aimed to investigate the characteristics of the patient group, possible changes in blood test and InBody test results, and to discover the current state and future direction of clinical use of Euphorbia kansui Radix or Melonis Calyx.

Methods: This study investigated patients who were hospitalized at Kyung-Hee University Korean Medicine Hospital for at least two days from 1 March 2016 to 1 March 2019, specifically evaluating patients aged 19 and over who underwent blood tests, including an electrolyte test and an InBody test before and after taking Euphorbia kansui Radix or Melonis Calyx.

Results: Among a total of 134 patients, 72 patients (53.7%) were treated with Euphorbia kansui Radix and 62 patients (46.3%) were treated with Melonis Calyx, in the context of previously diagnosed abnormal weight gain. Laboratory findings were that Na and K levels were significantly reduced in both groups. In an InBody test, body mass index (BMI), intracellular water, extracellular water, protein, mineral, and skeletal muscle were significantly reduced in both groups.

Conclusions: From these results, we suggest that, although Euphorbia kansui Radix and Melonis Calyx may not induce serious adverse effects, attention should be paid to the electrolyte level with the use of these treatments. In terms of syndrome differentiation, more clinical uses will be available in the future.

키워드

Euphorbia kansui radix; Melonis Calyx; syndrome differentiation; traditional chinese medicine; inbody test
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