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뇌혈관질환에 대한 다빈도 처방 한약의 임상적 유효성 : 후향적 연구

The Clinical Effectiveness of Frequently Used Herbal Medicines for Cerebrovascular Disease: A Retrospective Study

대한한방내과학회지 2019년 40권 6호 p.1063 ~ 1080
서희정 ( Seo Hee-Jeong ) - 부산대학교 한방병원 내과학교실

심소현 ( Shim So-Hyun ) - 부산대학교 한방병원 내과학교실
권정남 ( Kwon Jung-Nam ) - 부산대학교 한방병원 내과학교실
홍진우 ( Hong Jin-Woo ) - 부산대학교 한방병원 내과학교실
이인 ( Lee In ) - 부산대학교 한방병원 내과학교실

Abstract


Objectives: With the aging of the population, the incidence of a variety of diseases is increasing. Cerebrovascular disease is a major cause of mortality worldwide and therefore requires timely treatment and management. We aimed to evaluate the clinical effectiveness of herbal medicines in treating cerebrovascular disease by screening the most frequently prescribed herbal medicines and analyzing the clinical data of patients with cerebrovascular disease taking these medicines.

Methods: In this retrospective study, we analyzed the electronic medical records of patients with cerebrovascular disease who received herbal medication at the Pusan National University Korean Medical Hospital from 10 March 2010 to 31 March 2017. The inclusion criteria were as follows: diagnosis of cerebrovascular disease, use of frequently prescribed herbal medicines, available records of laboratory tests and functional evaluation that was conducted within two weeks before and after admission and discharge, and herbal medicine usage exceeding half the period of hospitalization.

Results: Of the total patients with cerebrovascular disease, the number of patients analyzed in this study was 49. There were some changes in the various variables examined after frequently used herbal medicines had been taken, such as complete blood count, liver function test, lipid test, and functional evaluation. No serious adverse events related to herbal medicine were found in this study.

Conclusions: We concluded that herbal medicines frequently used for cerebrovascular disease may have some clinical effectiveness. However, because of the retrospective nature of this study and only one hospital involved, the generalizability of our findings is limited.

키워드

cerebrovascular disease; herbal medicine; effectiveness; retrospective study
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