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위축성 위염에 대한 반하사심탕과 표준치료 병용요법의 최신 연구 동향

A Review of Recent Clinical Research about Banhasasim-tang Combined with Conventional Therapy on Atrophic Gastritis

대한한방내과학회지 2019년 40권 6호 p.1169 ~ 1178
이가영 ( Lee Ga-Young ) - 우석대학교 한의과대학 한의학과

안수빈 ( Ahn Su-Bin ) - 우석대학교 한의과대학 한의학과
정민정 ( Jeong Min-Jeong ) - 우석대학교 한의과대학 소아과학교실
장인수 ( Jang In-Soo ) - 우석대학교 한의과대학 한방내과학교실

Abstract


Objective: The purpose of this study was to investigate the effect of combined therapy with Banhasasim-tang and conventional treatment for atrophic Gastritis.

Methods: The study collected data of clinical studies of combined therapy with Banhasasim-tang and conventional treatment for atrophic gastritis. Electronic databases were used, including PubMed, Cochrane, CNKI, Wanfang, CINII, J-stage, NDSL, and OASIS. The main search terms included such as “Atrophic Gastritis”, “Banhasasim-tang”, “BanXia Xiexin Tang”. This study only included randomized controlled trials (RCTs) that adopted combined therapy with Banhasasim-tang and conventional treatment for atrophic gastritis.

Results: A total of 18 RCTs were selected. They all adopted combined therapy with Banhasasim-tang and conventional treatment for atrophic gastritis. In all the studies, the intervention group significantly improved the score of effective rate, and in the 8 studies, Hp negative conversion rate was significantly improved when Banhasasim-tang was taken.

Conclusion: Through the analysis of 18 RCTs, we found Banhasasim-tang combined with conventional therapy were more effective in the positive performance of atrophic gastritis than conventional therapy single contribution. However, due to the low quality of the selected studies and the lack of endoscopy, biopsy, follow-up observation, so there is a slight insufficient to prove its conclusion. Therefore, we hope that more systematic and diverse clinical studies will be conducted.

키워드

review; atrophic gastritis; Banhasasim-tang; Korean medicine
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