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Ethnobotany, Phytochemistry, and Pharmacology of Angelica decursiva Fr. et Sav.

Natural Product Sciences 2019년 25권 3호 p.181 ~ 199
 ( Ali Md Yousof ) - Concordia University Faculty of Arts and Science Department of Chemistry and Biochemistry

 ( Seong Su-Hui ) - Pukyong National University Department of Food and Life Science
 ( Jannat Susoma ) - Pukyong National University Department of Food and Life Science
 ( Jung Hyun-Ah ) - Chonbuk National University Department of Food Science and Human Nutrition
 ( Choi Jae-Sue ) - Pukyong National University Department of Food and Life Science

Abstract


Angelica decursiva Fr. et Sav. (Umbelliferae) has traditionally been used to treat different diseases due to its antitussive, analgesic, and antipyretic activities. It is also a remedy for thick phlegm, asthma, and upper respiratory infections. Recently, the leaf of A. decursiva has been consumed as salad without showing any toxicity. This plant is a rich in different types of coumarin derivatives, including dihydroxanthyletin, psoralen, dihydropsoralen, hydroxycoumarin, and dihydropyran. Its crude extracts and pure constituents possess antiinflammatory, anti-diabetic, anti-Alzheimer disease, anti-hypertension, anti-cancer, antioxidant, anthelmintic, preventing cerebral stroke, and neuroprotective activities. This valuable herb needs to be further studied and developed not only to treat these human diseases, but also to improve human health. This review provides an overview of current knowledge of A. decursiva metabolites and their biological activities to prioritize future studies.

키워드

Angelica decursiva; Umbelliferae; Coumarins; Bioactivity studies; Anti-inflammatory activity
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