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Two New Caffeoyl Threonate Esters from the Leaves of Toxicodendron vernicifluum

Natural Product Sciences 2019년 25권 4호 p.354 ~ 357
장재영 ( Jang Jae-Young ) - Chungbuk National University College of Pharmacy

안종훈 ( Ahn Jong-Hoon ) - Chungbuk National University College of Pharmacy
조양희 ( Jo Yang-Hee ) - Chungbuk National University College of Pharmacy
 ( Turk Ayman ) - Chungbuk National University College of Pharmacy
강소영 ( Kang So-Young ) - Chonnam National University Department of Aqualife Medicine
황방연 ( Hwang Bang-Yeon ) - Chungbuk National University College of Pharmacy
이미경 ( Lee Mi-Kyeong ) - Chungbuk National University College of Pharmacy

Abstract


Toxicodendron vernicifluum, also called as Rhus verniciflua is a deciduous tree belonging to Anacardiaceae family. Two new caffeoyl threonate esters, rhuseols A (1) and B (2), together with 5-O-(E)- caffeoylquinic acid methyl ester (3) were isolated from the leaves of T. vernicifluum. The structures of isolated compounds were established by using 1D and 2D NMR in combination with HR-ESI-MS. Compounds 1 - 3 showed DPPH radical scavenging effects with IC50 values of 47.9, 107.8 and 15.4 μM, respectively. Taken together, these compounds might contribute to the antioxidant properties of the leaves of T. vernicifluum, which will be useful for various oxidative stress mediated diseases.

키워드

Toxicodendron vernicifluum; caffeoyl threonate esters; antioxidant effect
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