잠시만 기다려 주세요. 로딩중입니다.

Effects of plant-derived natural products on inflammatory bone destructive disease

International Journal of Oral Biology 2019년 44권 4호 p.130 ~ 143
고선일 ( Ko Seon-Yle ) - Dankook University School of Dentistry Department of Oral Biochemistry

Abstract


Rheumatoid arthritis, osteoarthritis, and periodontal disease are bone destructive diseases mainly caused by inflammation. Various studies are being conducted to develop treatments for inflammatory bone destructive diseases. Many of these studies involve plant-derived natural compounds. In these studies, cell differentiation, signal transduction pathways, and bone resorption were measured at the cellular level. In disease-induced animal models, the amount of inflammatory mediators or matrix destructive enzymes and serum metabolic markers were measured. This study examined the effects of plant-derived natural compounds, such as flavonoids, on inflammatory bone destructive diseases. In addition, we structurally classified various substances used to maintain bone health and summarized the biological effects and related mechanisms of the components.

키워드

Polyphenol; Flavonoid; Arthritis; rheumatoid; Osteoarthritis; Periodontal diseases
원문 및 링크아웃 정보
등재저널 정보