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비만에서의 장내 미생물 무리의 역할

The Role of the Gut Microbiota in Obesity

대한내과학회지 2019년 94권 5호 p.410 ~ 413
김혜원 ( Kim Hae-Won ) - 순천향대학교 의과대학 내과학교실

백명기 ( Baeg Myong-Ki ) - 가톨릭관동대학교 의과대학 소화기내과학교실
김지현 ( Kim Jie-Hyun ) - 연세대학교 의과대학 소화기내과학교실

Abstract


Obesity is a critical target for public health interventions worldwide. There are many causes of obesity, and the importance of the gut microbiota in its pathogenesis has recently been recognized. The composition and function of the gut microbiota play a role in obesity and metabolic disease, yet the underlying mechanisms are unclear. Advances in our understanding of the link between obesity and the gut microbiota have suggested the potential of its manipulation for treating obesity. In this review, we summarize current knowledge of the interactions between the gut microbiota and obesity as well as the therapeutic potential of its modulation.

키워드

비만; 장내 미생물 무리
Obesity; Gastrointestinal microbiome
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