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노인 급성관동맥증후군 환자들의 항혈전치료

Antithrombotic Therapy for Elderly Patients with Acute Coronary Syndrome

임상노인의학회지 2019년 20권 2호 p.52 ~ 58
심민정 ( Shim Min-Jung ) - 차의과학대학교 분당차병원 심장내과

문재연 ( Moon Jae-Youn ) - 차의과학대학교 분당차병원 심장내과

Abstract


Ischemic heart disease is the leading cause of death in older people. In particular, more than one-third of myocardial infarction patients are aged 75 or older. Nonetheless, little attention has been given to the scientific assessment of antithrombotic treatment of acute coronary syndrome in older people. Despite the fact that older people with acute coronary syndrome increases, most randomized trials of antithrombotic treatment of acute coronary syndrome have been conducted excluding this population. For now, there is no establishment of scientific practice guideline of antithrombic treatment of acute coronary syndrome in older people. In clinical decision-making process, concerns of drastic hemorrhagic complications in older people often override the benefits of antithrombic treatment and lead to pursue more passive conservative treatment. The present article reviews various antithrombotic agents with an emphasis on older people with acute coronary syndrome by most recent updates derived from clinical trials and future perspectives.

키워드

Acute coronary syndrome; Anticoagulants; Elderly; Hemorrhage; Thrombosis
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