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An in vivo study comparing efficacy of 0.25% and 0.5% bupivacaine in infraorbital nerve block for postoperative analgesia

Journal of Dental Anesthesia and Pain Medicine 2019년 19권 4호 p.209 ~ 215
 ( Saha Aditi ) - Dr. D.Y. Patil Vidyapeeth Department of Oral and Maxillofacial Surgery

 ( Shah Sonal ) - Dr. D.Y. Patil Vidyapeeth Department of Oral and Maxillofacial Surgery
 ( Waknis Pushkar ) - Dr. D.Y. Patil Vidyapeeth Department of Oral and Maxillofacial Surgery
 ( Aher Sharvika ) - Dr. D.Y. Patil Vidyapeeth Department of Oral and Maxillofacial Surgery
 ( Bhujbal Prathamesh ) - Dr. D.Y. Patil Vidyapeeth Department of Oral and Maxillofacial Surgery
 ( Vaswani Vibha ) - Dr. D.Y. Patil Vidyapeeth Department of Oral and Maxillofacial Surgery

Abstract


Background: Pain is an unpleasant sensation ranging from mild localized discomfort to agony and is one of the most commonly experienced symptoms in oral surgery. Usually, local anesthetic agents and analgesics are used for pain control in oral surgical procedures. Local anesthetic agents including lignocaine and bupivacaine are routinely used in varying concentrations. The present study was designed to evaluate and compare the efficacy of 0.25% and 0.5% bupivacaine for postoperative analgesia in infraorbital nerve block.

Methods: Forty-one patients undergoing bilateral maxillary orthodontic extraction received 0.5% bupivacaine (n = 41) on one side and 0.25% bupivacaine (n = 41) on the other side at an interval of 7 d. The parameters evaluated for both the bupivacaine concentrations were onset of action, pain during procedure (visual analog scale score [VAS]), and duration of action. The results were noted, tabulated, and analyzed using the Wilcoxon signed rank test.

Results: The onset of action of 0.5% bupivacaine was quicker than that of 0.25% bupivacaine, but the difference was not statistically significant (P = 0.306). No significant difference was found between the solutions for VAS scores (P = 0.221) scores and duration of action (P = 0.662).

Conclusion: There was no significant difference between 0.25% bupivacaine and 0.5% bupivacaine in terms of onset of action, pain during procedure, and duration of action. The use of 0.25% bupivacaine is recommended.

키워드

Bupivacaine; Local Anesthesia; Postoperative Pain; Tooth Extraction
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