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Performance Evaluation of Infusion Systems for Red Blood Cell Transfusion

임상검사와정도관리 2019년 41권 3호 p.161 ~ 165
 ( Kim Min-Sun ) - University of Ulsan College of Medicine Asan Medical Center Department of Laboratory Medicine

김진석 ( Kim Jin-Seok ) - University of Ulsan College of Medicine Asan Medical Center Department of Laboratory Medicine
임은영 ( Lim Eun-Young ) - University of Ulsan College of Medicine Asan Medical Center Childrens Hospital Nursing Team
박홍철 ( Park Hong-Chul ) - University of Ulsan College of Medicine Asan Medical Center Department of Biomedical Engineering
 ( Hwang Sang-Hyun ) - University of Ulsan College of Medicine Asan Medical Center Department of Laboratory Medicine
 ( Oh Heung-Bum ) - University of Ulsan College of Medicine Asan Medical Center Department of Laboratory Medicine
 ( Ko Dae-Hyun ) - University of Ulsan College of Medicine Asan Medical Center Department of Laboratory Medicine

Abstract


Background: Transfusion in neonates and infants can be performed using an electromechanical infusion system that has appropriate accuracy in terms of flow rate, volume, and bolus. However, there are no infusion systems approved for transfusion in Korea. In this study, we evaluate the performance of two electromechanical infusion systems for transfusion in pediatric patients.

Methods: We tested two systems, Baxter and Terumo, using 9 units of leukocyte-filtered red blood cells. The blood samples were delivered through the systems at constant speeds of 10, 30, and 100 mL/hr, and the accuracy in terms of the delivered volume was estimated. Before and after infusion, hemoglobin, hematocrit, plasma hemoglobin, potassium, and lactate dehydrogenase levels were measured in each sample. The percentage of hemolysis (%Hemolysis) was calculated to evaluate the safety of the infusion systems.

Results: For Terumo, the mean error rate of the infused volume was less than 5%. We expect that Terumo can transfuse blood at a volume close to the set volume. Further, both infusion systems showed acceptable %Hemolysis levels (mean±standard deviation: Terumo, 0.14±0.04; Baxter, 0.17±0.06).

Conclusions: Both infusion systems can be used safely for transfusion in pediatric patients.

키워드

Electromechanical infusion system; Accuracy; Hemolysis
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