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전립선비대증 환자에서 방광경부의 조직 탄성도가 하부요로 증상에 미치는 영향

Impact of Bladder Neck Stiffness on Lower Unnary Tract Symptoms in Patient With Benign Prostatic Hyperplasia

대한비뇨기종양학회지 2019년 17권 3호 p.143 ~ 149
권종규 ( Kwon Jong-Kyou ) - 연세대학교 세브란스병원 비뇨의학과

정해도 ( Jung Hae-Do ) - 원광대학교 의과대학 산본병원 비뇨의학과
조강수 ( Cho Kang-Su ) - 연세대학교 의과대학 강남세브란스병원 비뇨기과학교실

Abstract


Purpose: We evaluated the impact of bladder neck stiffness on lower urinary tract symptoms in the patient with benign prostatic hyperplasia using elastography.

Material and Methods: A total of 384 patients divided into three different groups according to the bladder neck stiffness based on ultrasound with elastography. Patients age, prostate specific antigen (PSA), International Prostate Symptom Score (IPSS), prostate volumetric parameters, residual urine volume, and laboratory data were collected and compared among the three groups.

Results: Group 1 (n=121) showed low stiffness in both bladder neck adenoma. Group 2 (n=157) showed low to intermediated stiffness, and group 3 (n=106) showed significantly higher stiffness of bladder neck and adenoma compared to adjacent prostatic tissue. Significant differences among the 3 groups were found in the total prostate volume, transition zone volume, transition zone index, total IPSS, IPSS-voiding, IPSS-storage, residual urine volume, and quality of life. As the stiffness increased, prostate volumetric parameters, and residual urine volume were increased, and lower urinary tract symptoms became exacerbated. No significant difference was found in the patients' age and PSA.

Conclusions: Bladder neck stiffness affected the lower urinary tract symptoms and prostate volumetric parameters. These findings suggest that the change of bladder neck stiffness can be a novel parameter for the development of lower urinary tract symptoms/benign prostate hyperplasia.

키워드

Prostatic hyperplasia; Lower urinary tract symptoms; Elastography
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