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Effect of xylitol on dental caries prevention : a literature review

한국치위생학회지 2019년 19권 4호 p.449 ~ 465
 ( Lee Young-Eun ) - Daegu Health College Department of Dental Hygiene

 ( Kim Ji-Hye ) - Daegu Health College Department of Dental Hygiene
 ( Cho Min-Jeong ) - Kyungpook National University College of Science & Technology Department of Dental Hygiene
 ( Song Keun-Bae ) - Kyungpook National University School of Dentistry Department of Preventive Dentistry
 ( Choi Youn-Hee ) - Kyungpook National University School of Dentistry Department of Preventive Dentistry

Abstract


Xylitol is a sweetening agent used to prevent dental caries. It is formulated and consumed in various forms, and its use is recommended in particular for oral health. However, dental specialists are not familiar with xylitol or well-acquainted with the appropriate method to use it. Furthermore, the caries-prevention effect of xylitol has been controversial. Thus, in this study, we aimed to analyze previously published studies on the dental caries prevention effect of xylitol to verify its true effects and establish an appropriate method to use it. We analyzed 94 clinical research manuscripts obtained from domestic and international online databases and found that although 11 manuscripts reported no significant dental caries prevention effect of xylitol, most manuscripts reported dental caries prevention with xylitol. Compared to the manuscripts that reported dental caries prevention with xylitol, those are assessed lower amounts of xylitol or shorted consumption periods, and had dosage form that could not retain xylitol sufficiently long in the mouth, similar to milk. Thus, consumption of 5?11 g of xylitol in the form of gums, candies, or tablets over a long time period could effectively reduce the risk of dental caries. It has the advantage of ease of consumption, regardless of the gender, age, or disability of the person.

키워드

Clinical outcomes; Clinical trial; Dental caries; Guidelines; Xylitol
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