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Endoscopic Submucosal Dissection Followed by Concurrent Chemoradiotherapy in Patients with Early Esophageal Cancer with a High Risk of Lymph Node Metastasis

Clinical Endoscopy 2019년 52권 5호 p.502 ~ 505
 ( Kim Hee-Kyung ) - CHA University CHA Bundang Medical Center Digestive Disease Center

 ( Ko Weon-Jin ) - CHA University CHA Bundang Medical Center Digestive Disease Center
권창일 ( Kwon Chang-Il ) - CHA University CHA Bundang Medical Center Digestive Disease Center
 ( Song Ga-Won ) - CHA University CHA Bundang Medical Center Digestive Disease Center
 ( Yoo In-Kyung ) - CHA University CHA Bundang Medical Center Digestive Disease Center
 ( Song Ji-Hyun ) - CHA University CHA Bundang Medical Center Digestive Disease Center
 ( Kim Hak-Su ) - CHA University CHA Bundang Medical Center Digestive Disease Center
 ( Cho Joo-Young ) - CHA University CHA Bundang Medical Center Digestive Disease Center

Abstract


Endoscopic submucosal dissection is recommended as an alternative therapy for early esophageal cancer. However, achieving curative resection in this procedure remains controversial since precise prediction of lymph node metastasis can be difficult. Here, we present the preliminary results of endoscopic submucosal dissection followed by concurrent chemoradiotherapy for early esophageal cancer with a high risk of lymph node metastasis. From May 2006 to January 2014, six patients underwent concurrent chemoradiotherapy after endoscopic submucosal dissection with a median follow-up period of 63 months. No complications were encountered during concurrent chemoradiotherapy. Although local recurrence did not occur in all patients, two patients were diagnosed with metachronous cancer. Overall, the survival rate was 100%. Thus, endoscopic submucosal dissection followed by concurrent chemoradiotherapy may be a feasible treatment for early esophageal cancer in patients with a high risk of lymph node metastasis. Future prospective large-scale studies are warranted to confirm our results.

키워드

Early esophageal cancer; Concurrent chemoradiotherapy; Endoscopic submucosal dissection
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