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우안 하안검에 국한되어 발생한 Merkel 세포 종양

Merkel Cell Carcinoma Localized to Right Lower Eyelid

검안 및 콘택트렌즈학회지 2019년 18권 3호 p.96 ~ 99
김태훈 ( Kim Tae-Hoon ) - 고신대학교 의과대학 안과학교실

김창주 ( Kim Chang-Zoo ) - 고신대학교 의과대학 안과학교실
이승욱 ( Lee Seung-Uk ) - 고신대학교 의과대학 안과학교실
이상준 ( Lee Sang-Jun ) - 고신대학교 의과대학 안과학교실


Purpose: To report a case of Merkel cell carcinoma localized to the right lower eyelid treated by surgical resection alone.

Case summary: A 81-year-old woman visited the clinic with a painless and red-violet with 0.8 × 0.5 cm size tumor at the right lower eyelid, which developed 1 year ago. The patient complain that tumor begun to grow from 2 months ago. Surgical resection and biopsy were performed for treatment and diagnosis. We evaluated histologic exam using immunohistochemistry and it was positive for CD56 and chromogranin. Finally the patient was diagnosed as Merkel cell carcinoma of eyelid. The resection margin was not invaded and no additional resesction was performed. Local recurrence and metastasis were not observed for eight months.

Conclusions: Merkel cell carcinoma is highly aggressive neuroendocrine malignancy and occurrence is rare. If Merkel cell carcinoma is localized to the skin, surgical resection is the primary treatment option and adjuvant radiation therapy can be used. We report a case of Merkel cell carcinoma localized to lower eyelid that was surgically resected and showed good outcome without recurrence and metastasis.


Eyelid; Immunohistochemistry; Margins of excision; Merkel cell carcinoma
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