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50세 이상의 남성에서 대사증후군과 자가우울척도에 따른 우울 정도의 연관성

Association between Metabolic Syndrome and Severity of Depression Scored with Patient Health Questionnaire-9 in Men Older Than 50 Years

가정의학 2019년 9권 5호 p.467 ~ 470
이민식 ( Lee Min-Sik ) - 세림병원 가정의학과

Abstract


Background: This study aimed to evaluate the association between metabolic syndrome and depression severity based on the Patient Health Questionnaire 9 (PHQ-9) score in men aged >50 years.

Methods: In this study, we used data of 1,230 individuals from the Sixth Korea National Health and Nutrition Examination Survey (KNHANES VII-1) 2016 conducted by the Korea Centers for Disease Control and Prevention. We diagnosed metabolic syndrome in accordance with National Cholesterol Education Program-Adult Treatment Panel III guidelines using waist circumference, blood pressure, fasting serum triglyceride level, high-density lipoprotein cholesterol level, and fasting glucose level in men aged >50 years (mean± standard deviation: 64.6±8.8 years), and their PHQ-9 scores were classified as mild and severe (cutoff, 10).

Results: The mean waist circumference, fasting glucose level, triglyceride level, and high-density lipoprotein cholesterol level were 87.1±8.2 cm, 109.8±28.3 mg/dL, 155.9±123.9 mg/dL, and 46.5±12.2 mg/dL, respectively. The mean systolic and diastolic blood pressures were 124.7±15.9 mmHg and 76.2±10.7 mmHg, respectively. The mean body mass index, was 24.2±2.9 kg/m2. The prevalence of metabolic syndrome was 43.7%. The mean PHQ-9 score was 2.0±3.3. The prevalence of severe depression with a score of >10 was 4.2%. Metabolic syndrome and depression were related (P<0.05). The adjusted odds ratio for metabolic syndrome was 0.5 (95% confidence interval [CI], 0.3?0.9). However, age (95% CI, 0.9?1.0), sleep duration during weekdays (95% CI, 0.9?1.0), and sleep duration during weekends (95% CI, 0.9?1.0) were not related.

Conclusion: Metabolic syndrome was associated with depression in men aged >50 years in this study.

키워드

Metabolic Syndrome; National Institutes of Health; Depression; Patient Health Questionnaire; The Sixth Korea National Health and Nutrition Examination Survey
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