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Synthesis of Some Novel Thiazolyl - Azetidinone Hybrids

대한화학회지 2016년 60권 2호 p.107 ~ 110
 ( Ahn Chul-Jin ) - Changwon National University Department of Chemistry

 ( Hegde Hemant ) - Manipal Institute of Technology Department of Chemistry
 ( Shetty Nitinkumar S. ) - Manipal Institute of Technology Department of Chemistry

Abstract


A new series of hydrazino thiazolyl-2-azetidinone 4(a-i) derivatives were synthesized efficiently using benzylidene hydrazinyl thiazole derivatives 3(a-i). The precursors, benzylidene hydrazinyl thiazoles were prepared by reacting 4- fluoro phenacyl bromide with thiosemicarbazones 2(a-i). All the structures of the synthesized compounds were ascertained by IR, NMR and mass spectral analysis.

키워드

Azetidinone; Benzylidene hydrazinyl thiazole; 4-Flouro phenacyl bromide; Thiosemicarbazone
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