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Central venous disease in hemodialysis patients

Kidney Research and Clinical Practice 2019년 38권 3호 p.309 ~ 317
 ( Park Hoon-Suk ) - Catholic University College of Medicine Eunpyeong St. Mary’s Hospital Department of Internal Medicine

 ( Choi Joon-Sung ) - Catholic University College of Medicine St. Vincent’s Hospital Department of Radiology
 ( Baik Jun-Hyun ) - Catholic University College of Medicine St. Vincent’s Hospital Department of Radiology


Central venous disease (CVD) is difficult to treat and often resistant to treatment. In CVD, hemodialysis vascular access should sometimes be abandoned, or in serious cases, the patient's life may be threatened. Therefore, prevention is ideal. However, as the prevalence of chronic kidney disease (CKD) has increased steadily with population aging, CKD patients with a peripherally inserted central catheter (PICC) are encountered frequently. PICCs can cause CVD, and the basilic vein, which is regarded as the important last option for native arteriovenous fistula (AVF) creation in end-stage renal disease (ESRD) patients, is destroyed frequently after its use as the entry site of PICC. The most well-established risk factors for CVD are a history of central venous catheter (CVC) insertion and its duration of use. Therefore, to reduce the incidence of CVD, catheterization in the central vein (CV) should be minimized, along with its duration of use. In this review, we will first explain the basic territories of the CV and introduce its pathophysiology, clinical features, and advanced treatment options. Finally, we will emphasize prevention of CVD.


Central venous disease; Chronic kidney disease; Hemodialysis; Prevention
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