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대장 직장암에서 DNA Flow Cytometry 결과와 임상병리학적 특성 및 예후의 관계에 대한 연구

Flow Cytometric DNA Analysis in Colorectal Cancer and Its Relationship to Clinicopathological Features and Prognosis

대한대장항문학회지 1997년 13권 1호 p.23 ~ 30
최동호 ( Choi Dong-Ho ) - 한양대학교 의과대학 외과학교실

손태성 ( Son Tae-Sung ) - 한양대학교 의과대학 외과학교실
박영석 ( Park Young-Seok ) - 한양대학교 의과대학 외과학교실
백홍규 ( Baik Hong-Kyu ) - 한양대학교 의과대학 외과학교실
남영수 ( Nam Young-Soo ) - 한양대학교 의과대학 외과학교실
전규영 ( Jun Kyu-Young ) - 한양대학교 의과대학 일반외과학교실

Abstract


DNA flow cytometric analysis was performed on 42 colorectal cancers. DNA ploidy was diploid in 19 and aneuploid in 23 cases. There was no significant correlation between DNA ploidy and clinicopathological features such as primary site, histologic type, depth of invasion, lymph node metastasis, peritoneal seedings, lymphatic invasion and vascular invasion. In aneuploid group, which was divided into two groups, by the value of DNA index, there was no differences between two groups in prognosis and clinocoPathological features. Cumulative survival rates appeared to be more favorable in
patients with aneuploid tumors than patients with diploid tumors, but the difference was not statistically significant.

키워드

Flow Cytometry
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