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가족성 용종증 3예

Three Cases of Familial Adenomatous Polyposis

대한대장항문학회지 1997년 13권 2호 p.263 ~ 271
김진아 ( Kim Jin-Ah ) - 원광대학교 의과대학 내과학교실

서검석 ( Seo Geom-Seog ) - 원광대학교 의과대학 내과학교실
유경훈 ( Yoo Kyoung-Hoon ) - 원광대학교 의과대학 내과학교실
황호근 ( Hwang Ho-Geun ) - 원광대학교 의과대학 내과학교실
김제형 ( Kim Je-Hyung ) - 원광대학교 의과대학 내과학교실
이재승 ( Lee Jae-Seung ) - 원광대학교 의과대학 외과학교실
최석채 ( Choi Suck-Chei ) - 원광대학교 의과대학 내과학교실
김학철 ( Kim Haak-Cheoul ) - 원광대학교 의과대학 내과학교실
나용호 ( Nah Yong-Ho ) - 원광대학교 의과대학 내과학교실


Familial polyposis is a rare genetic disorder which the large intestine is diffusely carpeted by numerous adenomatous polyps. According to the recent studies, familial polyposis is a disease which produces polypoid lesions not only in the large intestine but also in the stomach, duodenum, ileum and jejunum. The natural course of extracolonic lesions is variable, but the colonic polyps are associated with high incidence of cancer. The risk of malignant change is virtually 100% if untreated. Thus when adenomatosis is noted, familial members at risk for familial adenomatous polyposis must be screened and prophylactic surgery performed to prevent inevitable colon cancer. Controversy exists about the most appropriate prophylactic treatment. Because of many disadvantages of ileostomy, total colectomy with ileorectal
anastomosis (ileoproctostomy) or total colectomy with rectal mucosa stripping and ileoanal anastomosis has become a more preferred approach. After ileorectal anastomosis, polyps in the retained rectum must be removed by
endoscopic polypectomy and rigorously followed by sigmoidoscopy every few months for prevention of polyp reccurence or malignant transformation. We experienced three cases of familial adenomatous polyposis and 2 of them were
treated successfully by preoperative colonoscopic polypectomy, total colectomy and ileop- roctostomy.


Familial Adenomatous Polyposis(FAP)
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