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만성변비환자에 있어 대장통과시간검사의 임상적 의의

Clinical Significance of Colon Transit Time Study in Patients with Chronic Constipation

대한대장항문학회지 1998년 14권 2호 p.235 ~ 240
성무경 ( Seong Moo-Kyung ) - 건국대학교 의과대학 외과학교실

주재식 ( Joo Jae-Sik ) - 한국보훈병원 일반외과

Abstract


Purpose: Measurement of colon transit time is well-known physiologic study for patients with chronic constipation. But information we get from it is frequently inconsistent with patient’s complaint. This study was designed to ascertain the actual significance of that measurement.

Methods: The subjects included two groups of patients with chronic constipation. One group consists of 32 patients(group A), The other group 36 patients(group B). Colon transit time study and defecographic examinations were done using previously described methods. But the former study was a little modified in group A, in which sodium phosphate enema was given at the previous day of oral intake of radio-opaque markers. Findings of colon transit time study and their relations to the defecographic results were compared with each other.

Results: As for the 5th day-findings of colon transit time, 6 cases(18.7%) were abnormal in group A and 3 cases(8.4%) in group B(statistically not different). As for the 3rd day-findings, 15 cases(46.9%) were abnormal in group A and 7 cases(19.5%) in group B( statistically different, p=0.0163). Defecographic findings showed 7 cases(21.9%) of outlet obstruction pattern in group A and 9 cases(25%) in group B. Correlations between these findings and those of colonic transit time studies were not proven statistically.

Conclusion: Colon transit time study with single marker bolus and the 5th day photography technique was considered not to reflect the actual conditions of patients with chronic constipation. But sodium phophate enema, given to patients before starting the study, seemed to enhance the accuracy of study.

키워드

Colon transit time study
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