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크론병의 외과적 치료

Surgical Treatment of Crohn’s Disease

대한대장항문학회지 2000년 16권 6호 p.415 ~ 422
김종관 ( Kim Jong-Kwan ) - 연세대학교 의과대학 외과학교실

이재길 ( Lee Jae-Gil ) - 연세대학교 의과대학 외과학교실
변창규 ( Byun Chang-Kyu ) - 연세대학교 의과대학 외과학교실
손승국 ( Sohn Seung-Kook ) - 연세대학교 의과대학 외과학교실
김남규 ( Kim Nam-Kyu ) - 연세대학교 의과대학 외과학교실
민진식 ( Min Jin-Sik ) - 연세대학교 의과대학 외과학교실

Abstract


Purpose: This study was undertaken to investigate the preoperative diagnosis, indication for operation, postoperative complication, postoperative medical treatment and recurrence rate in patients with Crohn’s disease who were treated with operation.

Methods: Forty patients with Crohn’s diseases had been operated on at the Department of Surgery, Yonsei University College of Medicine during the period from Jan 1986 to May 1999 and they were reviewed retrospectively. We studies symptoms, surgical indications, preoperative and postoperative treatments, involvement sites, types of operation and recurrence rate in Crohn’s disease.

Results: The male to female ratio was 1.5:1, and age distribution was from 8 to 69 years old with mean age of 33 years old. The duration of symptoms varies from within 1 day to above 10 years and most of them had within 1 month as 17 cases (42.5%). Symptoms are abdominal pain, hematochezia, anorexia, abdominal mass and diarrhea. The most frequent symptom was the abdominal pain as 85%. Crohn’s disease was diagnosed only 45% before operation, less than what we expected. In another hand it surprised us find out that tuberculosis enteritis was diagnosed as much as 20%. The most common indication of operation was medical treatment failure as 13 cases, and fistula was 7 cases, intestinal obstruction with stenosis and tumor were 6 cases each other. The involvement of small bowel was most common as 40%, and the most common operative findings were ulceration and fistula for 17 cases and 12 cases respectively. Small bowel cases were treated with segmental resection and anastomosis in all 16 cases. Large bowel cases were performed right hemicolectomy in 10 cases and total colectomy in 1 case. Both small and large bowel involvement cases, right hemicolectomy was done in 4 cases, right hemicolectomy and segmental resection of small bowel was done in 6 cases. The recurrence rate of postoperative medical treatment was 16% and 28% for 5 years and 10 years respectively. The
recurrence rate with no postoperative medical treatment was 13% and 26% for each 5 years and 10 years. There was no significantly difference in both groups.

Conclusion: The major surgical indications for Crohn’s disease were medical treatment failure, fistula and intestinal obstruction. Specially in Korea, differential diagnosis with tuberculosis enteritis was very important. Postoperative complication and recurrence rate has relatively low incidence. Our study suggest that postoperative medical treatment was controversial.

키워드

크론병;합병증;수술 적응증;수술 후 치료
Crohn’s disease;Complication;Surgical indication;Postoperative treatment
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