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우측 결장암 환자에서 복강경 및 개복수술 후 장기 생존율 비교

Comparison of Long-term Survival for Laparoscopic-assisted Surgery and Open Surgery for Right Colon Cancer: A Case- Control Study

대한대장항문학회지 2004년 20권 6호 p.384 ~ 390
최석경 ( Choi Suk-Kyung ) - 경북대학교 의과대학 외과학교실

이종호 ( Lee Jong-Ho ) - 경북대학교 의과대학 외과학교실
최규석 ( Choi Gyu-Seog ) - 경북대학교 의과대학 외과학교실

Abstract


Purpose: The aim of this study was to compare the long-term oncologic outcomes of laparoscopy assisted and open surgery for patients with right colon cancer.

Methods: From June 1996 to May 2000, 35 patients underwent curative surgery with a laparoscopic-assisted right hemicolectomy (LAC), and from among the patients who had curative open surgery, 35 patients with clinicopathologic characteristics comparable to those of the LAC group were selected and matched as a control group (OC). A comparative analysis of long-term survival and patterns of recurrence between these two groups was done.

Results: There were no statistical differences in demographic, laboratory and pathologic characteristics between the two groups. The mean follow-up period was 54.5 months. The overall five-year survival was 82.9% in the LAC group and 68.6% in the OC group, but was not statistically significant (P=0.17). Interestingly, the five-year survival of patients with TNM stage III tumors was significantly higher in the LAC group (84.2%) than in the OC group (52.6%) (P=0.04). There were no port-site recurrences or operative deaths.

Conclusions: The long-term oncologic outcomes of laparoscopic surgery for right-sided colon cancer were similar to those of open surgery. Interestingly, laparoscopic surgery for stage III tumors showed better survival than open surgery. However, a more large-scaled randomized study will be needed to clarify the oncologic safety of laparoscopic surgery for colon cancer. J Korean Soc Coloproctol 2004;20:384-390

키워드

복강경 수술;환자-대조군 연구;장기 생존율;종양학적 안정성
Laparoscopic surgery;Case-control study;Long- term survival;Oncologic safety
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