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후천성면역결핍증 환자에서 Cytomegalovirus 감염에 의해 발생한 직장의 궤양종괴형 종양

Ulcerofungating Rectal Mass Caused by Cytomegalovirus Infection in a Patient with AIDS

대한대장항문학회지 2007년 23권 4호 p.270 ~ 273
이상일 ( Lee Sang-Il ) - 충남대학교 의과대학 외과학교실

박준석 ( Park Jun-Seok ) - 분당서울대학교병원 외과
이택구 ( Lee Taek-Gu ) - 분당서울대학교병원 외과
김홍빈 ( Kim Hong-Bin ) - 분당서울대학교병원 내과
박영수 ( Park Young-Soo ) - 분당서울대학교병원 내과
이경호 ( Lee Kyoung-Ho ) - 분당서울대학교병원 영상의학과
강성범 ( Kang Sung-Bum ) - 분당서울대학교병원 외과

Abstract


Cytomegalovirus infection is a common complication in patients suffering from advanced acquired immunodeficiency syndrome. Cytomegalovirus infections of the gastrointestinal tract in human immunodeficiency-virus-positive patients tend to manifest as ulcerative lesions rather than as mass lesions. In this study, we describe a case of a mass lesion identified as cytomegalovirus proctitis in a human immunodeficiency-virus-positive patient, which had initially been thought to have an adenocarcinoma or a lymphoma. A 60-year-old man had an ulcerofungating mass in the rectum, which was initially detected via palpation. Findings of computerized tomography indicated a malignant mass, which was enhanced in the contrast image. An additional colonoscopy and biopsy were conducted for purposes of diagnosis. The histological examination revealed characteristic inclusion bodies within the nuclei of vascular endothelial cells in the ulcer bed. Immunohistochemical staining with anti-cytomegalovirus antibody confirmed the diagnosis of cytomegalovirus infection. The patient’s anorectal lesion had subsided after the initiation antiviral treatments. The diagnosis of cytomegalovirus infection in human immunodeficiency-virus- positive patients occasionally proves rather difficult. Cytomegalovirus infection had induce the formation of mass lesions in immunocompromised patients. J Korean Soc Coloproctol 2007;23:270-273

키워드

사이토메갈로바이러스;직장종괴;후천성면역결핍증
Cytomegalovirus infection;Rectum;Acquired immuno-deficiency syndrome
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