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결장직장암의 수술 전 병기 결정을 위한 양전자방출 단층촬영의 유용성

Positron Emission Tomography (PET)- Computed Tomography (CT) for Preoperative Staging of Colorectal Cancers

대한대장항문학회지 2008년 24권 3호 p.201 ~ 206
유중재 ( Yoo Joong-Jae ) - 고신대학교 의과대학 외과학교실

이승현 ( Lee Seung-Hyun ) - 고신대학교 의과대학 외과학교실
안병권 ( Ahn Byung-Kwon ) - 고신대학교 의과대학 외과학교실
백승언 ( Baek Sung-Uhn ) - 고신대학교 의과대학 외과학교실
이석모 ( Lee Seok-Mo ) - 고신대학교 의과대학 핵의학교실

Abstract


Purpose: The purpose of this study is to evaluate the usefulness of positron emission tomography (PET)- computed tomography (CT) for preoperative tumor staging in cases of colorectal cancer.

Methods: Between July 2006 and September 2007, seventy-six patients with a diagnosis of colorectal cancer (43 males and 33 females; mean age: 60.4±10.13 years; range: 34∼82 years) selected prospectively were studied for staging by using Chest X-ray, abdominal CT and PET-CT.

Results: The sensitivities and the specificities for N-staging were 76.9% and 35.1% for CT, 61.8% and 66.7% for PET-CT, and both procedures showed a relatively low diagnostic accuracy (CT 57.9%, PET-CT 61.8%). In the PET-CT alone, six distant metastatic lesions and four multiple primary malignancies were found. The locations of the distant metastases were the liver, the axillary node, the common iliac node, the subclavicular node, the peritoneum, and the lung. The locations of the multiple primary maligancies in extracolonic sites were 3 in the thyroid and 1 in the nasopharynx.

Conclusions: For N-staging, preoperative PET-CT is no more useful than CT, but PET-CT is required before surgery to find lesions that cannot be found with conventional studies. J Korean Soc Coloproctol 2008;24:201-206

키워드

양전자방출 단층촬영;결장직장암;병기결정
Positron emission tomography; Colorectal cancer; Staging
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