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Acute Hyponatremia With Seizure and Mental Change After Oral Sodium Picosulfate/Magnesium Citrate Bowel Preparation

대한대장항문학회지 2014년 30권 6호 p.290 ~ 293
 ( Cho Young-Sun ) - Wallace Memorial Baptist Hospital Department of Internal Medicine

 ( Nam Kyung-Min ) - Wallace Memorial Baptist Hospital Department of Internal Medicine
 ( Park Jang-Ho ) - Wallace Memorial Baptist Hospital Department of Internal Medicine
 ( Byun Sang-Hwan ) - Wallace Memorial Baptist Hospital Department of Internal Medicine
 ( Ryu Jin-Suck ) - Wallace Memorial Baptist Hospital Department of Internal Medicine
 ( Kim Hyun-Ju ) - Wallace Memorial Baptist Hospital Department of Internal Medicine

Abstract


Sodium picosulfate/magnesium citrate (Picolight Powder), which is used as a bowel preparation for the colon and the rectum, can cause a severe electrolyte imbalance like hyponatremia. When hyponatremia gets severe or occurs rapidly, it can lead to death due to associated complications. We have experienced a case of hyponatremia associated with seizure and loss of consciousness in a 76-year-old woman, who took sodium picosulfate/magnesium citrate as a bowel preparation for colonoscopy. She was taking thiazide and synthroid for the treatment of hypertension and hypothyroidism, respectively, and she had other underlying medical conditions such as a history of seizure and dementia. Following the diagnosis of hyponatremia, we used an intravenous injection of 3% NaCl to normalize the sodium level in her serum, and her associated symptoms soon disappeared.

키워드

Picosulfate sodium; Bowel preparation; Hyponatremia; Seizures; Colonoscopy
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