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ritoneal Metastatic Goblet-Cell Carcinoid Tumor Treated With Cytoreductive Surgery and Intraperitoneal Chemotherapy

대한대장항문학회지 2015년 31권 2호 p.74 ~ 78
 ( Youn Sang-Il ) - Dankook University College of Medicine Department of Surgery

 ( Namgung Hwan ) - Dankook University College of Medicine Department of Surgery
 ( Yun Jeong-Seok ) - Dankook University College of Medicine Department of Surgery
 ( Park Yun-Jun ) - Dankook University College of Medicine Department of Surgery
 ( Park Dong-Guk ) - Dankook University College of Medicine Department of Surgery

Abstract


We report a case of a goblet-cell carcinoid tumor of the appendix which metastasized to the peritoneum and was treated by using cytoreductive surgery (CRS) with intraperitoneal chemotherapy. A 47-year-old male presented with chronic constipation and was diagnosed as having a rectal adenocarcinoma with a signet-ring-cell component under colonoscopy. Computed tomography suggested peritoneal metastases with diffuse nodular parietal peritoneal thickening of the entire abdomen and focal invasion of the upper rectum by a seeding mass. CRS with intraperitoneal chemotherapy was done under the diagnosis of a rectal adenocarcinoma with peritoneal metastases. The pathologic diagnosis was a goblet-cell carcinoid tumor of the appendix with peritoneal metastasis. The histological discrepancy between a peritoneal metastatic mass and a rectal mass was due to the mixed histological pattern of a goblet-cell carcinoid tumor. A metastatic mass may not share identical immunohistochemical characteristics from its origin. This histologic discrepancy necessitates caution in diagnosing a distant metastasis of a goblet-cell carcinoid tumor.

키워드

Appendix; Carcinoid tumor; Goblet cells; Peritoneal neoplasms; Intraperitoneal infusion
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