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강원도 농촌 지역에서 전립선비대증의 양상 및 삶의 질에 미치는 영향에 대한 연구

Benign Prostatic Hyperplasia: Its Feature and Impact on the Quality of Life in Rural Area of Kangwon Province

대한비뇨기과학회지 1999년 40권 4호 p.446 ~ 452
김한권/Han Gwun Kim
박종연/정승문/이성희/이상열/Jong Yeon Park/Seung Mun Jung/Seung Hee Lee/Sang Youl Lee

Abstract

결론
50세 이상의 남성 250명을 대상으로 시행한 연구 결과 이중 중등도 이상의 증상을 호소한
군은 78.71%이었으며 경직장초음파로 측정 한 전립선 평균용적은 28.27㎝3
었으며 각 연령군간의 전립선용적은 통계학적으로 유의한 차이가 없었다. 최고요속이 15㎖
/sec 미만인 군은 15㎖/sec이상인 군에 비하여 배뇨량, 삶의 질, 전립선증상점수 등에서 유
의한 차이를 보여 요류측정술의 지표가 전립선증 환자의 평가에 대단히 중요함을 알 수 있
었다.
증상점수가 경증군인 경우가 다른 군에 비하여 유의한 전립선비대가 있을 가능성이 적었
으며 증상점수를 결정하는 인자로서는 평균요속이 가장 중요하였다. 전립선용적은 요류속도
및 증상점수를 결정하는 데는 중요한 역할을 하지 않아 전립선증 환자를 평가하는데 직장수
지검사로 촉지되는 전립선의 크기만으로 평가하기보다는 자세한 문진과 이학적 검사가 더욱
중요하다고 할 것이다.

Purpose : We studied 250 men who are over 50 years of age to evaluate the feature
of benign prostatic hyperplasia and its impact on quality of life in rural areas of the
Korea.
Materials and Methods : Two hundred fifty men participated in this study. Urinalysis,
urine culture, uroflowmetry, digital rectal examination and serum PSA were examined on
all the participants. Transrectal ultrasonography(TRUS) were performed in 234 men.
Results : Of these 250 men, symptom prevalence was 78.71%. The age distributions of
50-59, 60-69, 70-79 and ≥80 years of age were 91, 111, 43 and 5 men
respectively(mean 62.4). The mean prostatic volumes for 50-59, 60-69, 70-79 and ≥ 80
years of age group were 2.33㎝3, 29.95㎝3, 28.89㎝
3 and 33.55㎝3. Of these, its volume difference was not
statistically significant. Of 250 men, mildly symptomatic group(IPSS≤7) was 22.5%,
moderately symptomatic group(8≤IPSS≤19) 43%, and severely symptomatic group(IPSS
≥20) 34.5%. Severely symptomatic group showed higher mean age(p=0.0478), lower
maximal flow rate(MFR)(p=0.024) and average flow rate(AFR)(p=0.003). Mildly
symptomatic group showed smaller prostatic volume(p=0.013). Mean quality of life score
for mildly, moderately, and severely symptomatic group were 2.09, 3.50, and 4.51 points,
the score of which showed statistical difference(p<0.001). On comparison between the
group of MFR<15㎖/sec and the group of MFR≥15㎖/sec, statistical difference for the
mean age(p<0.001), voided volume(p<0.001), QOL(p=0.02) and symptom score(p=0.002)
was found. But no difference was found in prostatic volume(p=0.261). MFR, AFR and
voided volume did not show significant correlation with prostatic volume. But serum
PSA level was strongly correlated with prostatic volume. The AFR was a greatest
determinant to symptom score in multiple regression analysis.
Conclusions : The symptom prevalence in rural areas of the Korea is not any less
than that of western society. This study shows that it too has a great impact on the
quality of life in rural Korea. The prostatic volume itself had no significance on
symptom score nor uroflowmetric parameters. The uroflowmetric parameter such as
MFR is more important in evaluating symptomatic patients than prostatic volume itself.

키워드

Benign prostatic hyperplasia; Ultrasonography; Symptom score;
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