잠시만 기다려 주세요. 로딩중입니다.

The Second-to-Fourth Digit Ratio in Cryptorchidism: A Case-Control Study

대한비뇨기과학회지 2014년 55권 2호 p.140 ~ 144
 ( Hwang Ha-Wook ) - Eulji University School of Medicine Eulji Hospital Department of Urology

 ( Jo Hyun-Wook ) - Eulji University School of Medicine Department of Urology
 ( Kim Tae-woo ) - Eulji University Hospital Department of Nursing
 ( Yu Dae-Seon ) - Eulji University School of Medicine Eulji Hospital Department of Urology
 ( Park Jin-Sung ) - Eulji University School of Medicine Department of Urology
 ( Kim Dae-Kyeng ) - Eulji University School of Medicine Eulji Hospital Department of Urology
 ( Woo Seung-Hyo ) - Eulji University School of Medicine Department of Urology
 ( Yun Bong-Ju ) - Eulji University Hospital Department of Nursing

Abstract


Purpose: The homeobox (Hox) genes a and d controlling limb and genital development influence the digit ratio and the fetal production of testicular androgen, which may result in testicular descent in boys. To assess whether the digit ratio reflects disease status, we investigated the second and fourth finger lengths in children with cryptorchidism, in children with hydrocele as a disease control, and in healthy controls (boys and girls).

Materials and Methods: One hundred ninety-six children (46 with cryptorchidism, 50 with hydrocele, 50 healthy boys, and 50 healthy girls) who were 6 to 23 months of age were prospectively enrolled. Digit lengths were measured by 2 investigators, and the mean value was recorded.

Results: The second-to-fourth digit ratios (2D:4Ds) of the left hand in the cryptorchidism group, hydrocele group, healthy boys, and healthy girls were 0.958, 0.956, 0.950, and 0.956, respectively. The 2D:4D values of the right hand were 0.946, 0.945, 0.952, and 0.969, respectively. The right and left 2D:4D ratios were not significantly different among groups. The 2D:4D of both hands was not related to age, weight, or height.

Conclusions: According to these results, the 2D:4D was not significantly different in boys with cryptorchidism than in boys with hydrocele or in healthy controls (boys and girls) and failed to reflect disease conditions in the infant period.

키워드

Anthropometry; Child; Cryptorchidism; Fingers
원문 및 링크아웃 정보
   
등재저널 정보
KCI
KoreaMed
KAMS