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Meperidine 점적주입의 진통완화효과

Effect of Intravenous Infusion of Meperidine on Relief of labor Pain

대한산부인과학회지 1971년 14권 10호 p.35 ~ 39
전정일/Chun, Chung Il
최명학/문재민/진성대/Moon, Jae Min/Choi, Myong Hack/Chin, Sung Dae

Abstract


Obstetric analgesia and anesthesia have much been developed since 1847 when. Dr. Simpson had first, started obstetric anesthesiiin his practice. However, there are still many problems to. be solved.
Meperidine, one of the well known analgesic has long been used as a single dose of intramuscular oar intravenous route with being accompanied by some - difficulties for controlling dosage.
Intravenous infusion of meperidine was used and it was accompained by
En excellent analgesic effect with constant level in the blood. Intravenous infusion of meperidine was used to 20 primigravidas and 20 multiparas and it´s results wers as follow;
1. The mean dosage of meperidine for maintaining ideal analgesic effect was 1.29 mg/kg/hr.
2. The incidence of good, moderate and poor analgesic effects were 90%, 7.5% and 2.5% respectively.
3. Intravenous infusion of meperidine did not affect the duration of labor.
4. The frequency of uterine contraction seems to be -decreased but it did not affect the intensity and duration of uterine contraction.,
5. The condition of newborns were excellent and 95% of newborns had an apgar score of 7-10 at one minute and all newborns had 7-10 at 5- minutes. 6. Intravenous infusion of meperidine did not affect uterine contraction, involution and bleeding in postpartum.

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